师资
个人简介：
医学院讲席教授。先后在第三军医大学烧伤研究所和创伤烧伤与复合伤国家重点实验室从事烧伤和创面修复临床治疗与转化研究，主要研究微环境与创面修复，以及微环境营造促进创面原位修复再生的新技术和新材料的转化，在国际和国内期刊发表论文350余篇，牵头制定20余项全国临床专家共识指南，发明专利7件，主、参编专著35部，获国家科技进步二等奖4项等各级科技成果奖10余项，严重烧伤早期损害的救治技术被国家卫生部列为适宜卫生技术推广项目, 发明的施加方向性电场创面敷料已申请创新医疗器械注册。 先后担任中华医学会烧伤外科分会主任委员、中华烧伤杂志总编辑、《Burns》杂志高级编委、中国老年医学学会烧创伤分会会长、中国生物材料学会烧创伤创面修复材料分会主任委员、国家卫生健康委能力建设和继续教育创面修复科专家委员会副主任委员，参与国家自然科学基金学科评审和国家科技进步奖评审。培养硕士和博士研究生70余名。
为国家杰出青年科学基金获得者，首届新世纪百千万人才工程国家级人选，全国优秀科技工作者，获中国医师奖、烧伤医学终身成就奖。
教育背景：
1978.09-1983.07 第三军医大学军医系学员，获医学学士学位
1983.08-1986.07 第三军医大学烧伤外科学硕士研究生，获医学硕士学位
1986.08-1989.11 第三军医大学烧伤外科学博士研究生，获医学博士学位
工作经历：
1989.12-1997.04 第三军医大学烧伤研究所主治医师，讲师，副主任医师，副教授，主任医师，教授，博士导师，副所长
1997.05-1999.06 美国德克萨斯大学加尔维斯顿医学分校 博士后
1999.07-1999.11 第三军医大学烧伤研究所副所长，主任医师，教授，博士导师
1999.12-2010.08 第三军医大学烧伤研究所所长，主任医师，教授，博士导师
2003.03-2005.05 创伤、烧伤与复合伤国家重点实验室副主任 博士导师，主任医师，教授，
2005.06-2017.07 创伤、烧伤与复合伤国家重点实验室主任，主任医师，教授， 博士导师
2006.06-2010.08 第三军医大学西南烧伤专科医院院长
2010.08-2022.05 第三军医大学烧伤研究所名誉所长，主任医师，教授，博士导师
2017.07-2022.05创伤、烧伤与复合伤国家重点实验室主任顾问，主任医师，教授，博士导师
2022.05- 南方科技大学医学院创面修复与再生医学研究所 讲席教授
2022.05- 南方科技大学医院创面修复科 主任医师、教授，科主任
获奖情况及荣誉：
获国家科技进步二等奖4项（第一完成人2项）、省部级科技进步一等奖3项，黎鳌烧伤医学奖一等奖1项。
首批新世纪百千万人才工程国家级人选、全国优秀科技工作者、中国医师奖、中国科协求是杰出青年实用工程奖、烧伤医学终身成就奖、国家有突出贡献中青年专家、全军杰出专业技术人才、重庆市杰出专业技术人才、重庆市首席医学专家等。
研究领域：
创面微环境与修复，营造促进创面原位修复再生的新技术和新材料研发与临床评价，以及创面修复临床技术。
学术任职：
中华医学会理事会（第23-25届）理事、中华医学会烧伤外科学分会（第七届）主任委员、中华烧伤杂志第三和第四届总编辑、中国老年医学学会烧创伤分会会长、中国生物材料学会烧创伤创面临床应用分会主任委员、中国研究型医院学会生物材料临床应用专业委员会主任委员、国家卫生健康委能力建设和继续教育创面修复科专家委员会副主任委员、全军第七和第八届烧伤与整形外科专业委员会主任委员、第四军医大学军事口腔医学国家重点实验室学术委员会委员、第三军医大学创伤烧伤与复合伤国家重点实验室学术委员会委员、暨南大学再生医学教育部重点实验室学术委员会委员、海南医科大学教育部重点实验室学术委员会委员，以及多个杂志副主编和编委等。
发表论文（部分）：
1 Yan Shi,Shang Wang, Ronghua Yang, Zhenmin Wang, Weiwei Zhang, Hongwei Liu#, and Yuesheng Huang#. ROS Promote Hypoxia-Induced Keratinocyte Epithelial-Mesenchymal Transition by Inducing SOX2 Expression and Subsequent Activation of Wnt/-Catenin. Oxidative Medicine and Cellular Longevity, 2022, Article ID 1084006.
2 Yan-hai Feng, Ling-fei Li, Qiong Zhang, Jun-hui Zhang, Yao Huang, Yan-ling Lv, Jie-Zhi Jia, Dongxia Zhang, Jiong-Yu Hu# and Yue-Sheng Huang#. Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related Pyroptosis. Cell Death Discovery, 2021, 7:213.
3 Yao Huang, Yanhai Feng, Lin Cui, Lei Yang, Qiong Zhang, Junhui Zhang,Xupin Jiang, Xingyue Zhang, Yanling Lv, Jie-Zhi Jia, Dong-Xia Zhang#，Yue-Sheng Huang#. Autophagy-Related LC3 Accumulation nteracted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes. Front. Cell Dev. Biol. , 2021, 9: 679637.
4 Wei Jinyu, Lin Jiezhi, Zhang Junhui, Tang Di, Xiang Fei, Cui Lin, Zhang Qiong, Yuan Hongping, Song Huapei, Lv Yanling, Jia Jiezhi, Zhang Dongxia #, Huang Yuesheng#, TRPV1 Activation Mitigates Hypoxic Injury in Mouse Cardiomyocytes by Inducing Autophagy Through the AMPK Signaling Pathway. Am J Physiol Cell Physiol. 2020; 318(5):C1018-C1029.
5 Yi Liang, Hao Tian, Jie Liu , YanLing Lv, Yuan Wang, JiaPing Zhang#, YueSheng Huang#. Application of stable continuous external electric field promotes wound healing in pig wound model. Bioelectrochemistry, 2020, 135: 107578.
6 Xiaodong Lan, Zhiyong Huang, Ziming Tan, Zhenjia Huang, Dehuai Wang#，Yuesheng Huang#. Nebulized heparin for inhalation injury in burn patients: a systematic review and meta-analysis. Burns & Trauma, 2020, 8: tkaa015
7 Zhang X, Li L, Zhang Q, Wei Q, Lin J, Jia J, Zhang J, Yan T, Lv Y, Jiang X, Zhang P, Song H, Zhang D#，Huang Y# . CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions. Front. Cell Dev. Biol. , 2020, 8: 191.
8 Lin Cui, Li-Ping Zhao, Jing-Ying Ye, Lei Yang, Yao Huang, Xu-Pin Jiang, Qiong Zhang, Jie-Zhi Jia, Dong-Xia Zhang#, Yuesheng Huang#. The Lysosomal Membrane Protein Lamp2 Alleviates Lysosomal Cell Death by Promoting Autophagic Flux in Ischemic Cardiomyocytes. Front. Cell Dev. Biol., 2020, 8: 31.
9 Xupin Jiang, Miao Teng, Ran Ji, Dongxia Zhang, Ze Zhang, Yanling Lv, Qiong Zhang, Jiaping Zhang#, Yuesheng Huang#. CD9 regulates keratinocyte differentiation and motility by recruiting Ecadherinto the plasma membrane and activating the PI3K/Akt pathway. BBA - Molecular Cell Research 2020; 1867 :118574
10 Junhui Zhang, Can Zhang, Xupin Jiang, Lingfei Li, Dongxia Zhang, Di Tang, Tiantian Yan, Qiong Zhang,Hongping Yuan, Jiezhi Jia, Jiongyu Hu, Jiaping Zhang，Yuesheng Huang*. Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration. Cell Death and Disease 2019；10:234.
11 Tiantian Yan, Xupin Jiang, Guoan Lin, Di Tang, Junhui Zhang, Xiaowei Guo, Dongxia Zhang, Qiong Zhang, Jiezhi Jia, Yuesheng Huang*. Autophagy is required for the directed motility of keratinocyte driven by electric fields. FASEB J . 2019; 33(3): 3922-3935.
12 Lei Yang, Liping Zhao, Lin Cui, Yao Huang, Jingying Ye, Qiong Zhang, Xupin Jiang, Dongxia Zhang#, Yuesheng Huang#. Decreased α-tubulin acetylation induced by an acidic environment impairs autophagosome formation and leads to rat cardiomyocyte injury. J Mol Cell Cardiol. 2019; 127: 143-153.
13 Lingfei Li, Xingyue Zhang, Qiong Zhang, Jiezhi Jia,Junhui Zhang,Dongxia Zhang, Huapei Song, Bing Chen , Jiongyu Hu# , Yuesheng Huang#. Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury.Oxidative Medicine and Cellular Longevity 2019；Article ID 6428924.
14 Junhui Zhang, Lingfei Li, Qiong Zhang, Xu Yang, Can Zhang, Xingyue Zhang, Dongxia Zhang, Yanling Lv, Huapei Song, Bing Chen, Yao Liu, Jiongyu Hu#, Yuesheng Huang#. Phosphorylation of Microtubule-Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation. Front. Pharmacol. 2019;10:368.
15 Li L, Zhang J, Zhang Q, Zhang D, Xiang F, Jia J, Wei P, Zhang J, Hu J#， Huang Y#. High Glucose Suppresses Keratinocyte Migration Through the Inhibition of p38 MAPK/Autophagy Pathway. Front. Physiol. 2019;10:24.
16 Lingfei Li, Junhui Zhang, Qiong Zhang, Yuesheng Huang#. Jiongyu Hu#. Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction. Burns & Trauma 2019; 7:8.
17 Fei Xiang, Si-yuan Ma, Yan-ling Lv, Dong-xia Zhang, Hua-pei Song，Yue-sheng Huang*.Tumor necrosis factor receptor-associated protein 1 regulates hypoxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II. Burns& Trauma 2019; 7:16.
18 Junhui Zhang, Lingfei Li, Qiong Zhang, Wensheng Wang, Dongxia Zhang, Jiezhi Jia, Yanling Lv, Hongping Yuan, Huapei Song, Fei Xiang, Jiongyu Hu#, Yuesheng Huang#. Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation. Int J Biol Sci.，2019; 15(9): 1962-1976.
19 Lingfei Li, Qiong Zhang, Xingyue Zhang, Junhui Zhang, Xuefeng Wang, Jun Ren, Jiezhi Jia, Dongxia Zhang, Xupin Jiang, Jiaping Zhang, Hao Mei, Bing Chen, Jiongyu Hu#, Yuesheng Huang#. Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice. EBioMedicine 2018；37:221-235.
20 Hao Tian, Liangxi Wang, WeiguoXie, Chuanan Shen, Guanghua Guo, Jiaqi Liu, Chunmao Han, Licheng Ren, Yi Liang, Yong Tang, Yuan Wang, Weifang Yin, Jiaping Zhang# , Yuesheng Huang#. Epidemiologic and clinical characteristics of severe burn patients: results of a retrospective multicenter study in China, 2011-2015. Burns & Trauma 2018; 6(2): 140-150.
21 Junhui Zhang，Dongxia Zhang，Tiantan Yan，Xupin Jiang，Can Zhang， Liping Zhao，Lingfei Li，Di Tang，Qiong Zhang，Jiezhi Jia，Jiaping Zhang，Yuesheng Huang #. BNIP3 promotes the motlity and migraton of keratnocyte under hypoxia. Experimental Dermatology 2017; 26: 416–422.
22 Di Tang, Tiantian Yan, Junhui Zhang, Xupin Jiang, Dongxia Zhang, Yuesheng Huang*. Notch1 Signaling Contributes to Hypoxia-induced High Expression of Integrin β1 in Keratinocyte Migration. Scientific Reports 2017; 7:43926.
23 Tiantian Yan, Junhui Zhang, Di Tang, Xingyue Zhang, Xupin Jiang, Liping Zhao, Qiong Zhang, Dongxia Zhang, Yuesheng Huang*. Hypoxia Regulates mTORC1-Mediated Keratinocyte Motility and Migration via the AMPK Pathway. PLoS ONE， 2017; 12(1): e0169155.
24 Tiantian Yan, Xupin Jiang, Xiaowei Guo, Wen Chen, Di Tang, Junhui Zhang, Xingyue Zhang, Dongxia Zhang, Qiong Zhang, Jiezhi Jia, Yuesheng Huang*. Electric field-induced suppression of PTEN drives epithelial-to -mesenchymal transition via mTORC1 activation. J Dermatol Sci， 2017; 85(2): 96–105.
25 Chen Wen，Jiang Youzhao， Han Jian， Hu Jiongyu，He Ting， Yan Tiantian，Huang Na，Zhang Qiong，Mei Hao，Liao Yong，Huang Yuesheng#，Chen, Bing#. Atgl deficiency induces podocyte apoptosis and leads to glomerular filtration barrier damage. FEBS Journal, 2017; 284(7): 1070-1081.
26 Liping Zhao, Lin Cui, Xupin Jiang, Junhui Zhang, Minghua Zhu, Jiezhi Jia, Qiong Zhang, iaping Zhang, Dongxia Zhang#, Yuesheng Huang#. Extracellular pH regulates autophagy via the AMPK–ULK1 pathway in rat cardiomyocytes. FEBS Letters，2016；590 ：3202–3212 （IF 4.124）
27 Fei Xiang, Si-Yuan Ma, Dong-Xia Zhang, Qiong Zhang, Yue-Sheng Huang*. Tumor necrosis factor receptor-associated protein 1 improveshypoxia-impaired energy production in cardiomyocytes through increasing activity of cytochrome c oxidase subunit II. Int J Biochem Cell Biol , 2016；79：239–248.
28 Zhang Dong-Xia, Zhang Jia-Ping, Hu Jiong-Yu, Huang Yue-Sheng*. The potential regulatory roles of NAD+ and its metabolism in autophagy. Metabolism: Clinical and Experimental. 2016，65: 454–462.
29 Xiaodong Lan, Lingfei Li, Jiongyu Hu, Qiong Zhang, Yongming Dang#, Yuesheng Huang#. A Quantitative Method for Microtubule Analysis in Fluorescence Images. Microsc. Microanal，2015， 21（12）：1582–1590.
30 Xiaowei Guo, Xupin Jiang, Xi Ren, Huanbo Sun, Dongxia Zhang, Qiong Zhang, Jiaping Zhang# ,Yuesheng Huang#. The Galvanotactic Migration of Keratinocytes is Enhanced by Hypoxic Preconditioning. Scientific Reports 2015; 5:10289.
31 Yongming Dang, Xiaodong Lan, Qiong Zhang, Lingfei Li, Yuesheng Huang*. Analysis of Grayscale Characteristics in Images of Labeled Microtubules from Cultured Cardiac Myocytes. Microsc. Microanal.2015, 21, 334–342.
32 Xupin Jiang, Dongxia Zhang, Hengshu Zhang, Yuesheng Huang, Miao Teng. Role of Ran-regulated nuclear-cytoplasmic trafficking of pVHL in the regulation of microtubular stability-mediated HIF-1a in hypoxic cardiomyocytes. Sci Rep, 2015; 5 : 9193.
33 Lingfei Li, Jiongyu Hu, Ting He, Qiong Zhang, Xu Yang, Xiaodong Lan, Dongxia Zhang, Hao Mei, Bing Chen#, Yuesheng Huang#. P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury. Sci Rep 2015; 5 : 8895.
34 Ting He, Jiongyu Hu, Guangning Yan, Lingfei Li, Dongxia Zhang, Qiong Zhang, Bing Chen#, Yuesheng Huang#. Pigment epithelium-derived factor regulates microvascular permeability through adipose triglyceride lipase in sepsis.Clin Sci 2015; 129: 49–61.
35 Xupin Jiang, Xiaowei Guo, Xue Xu, Miao Teng, Chong Huang, Dongxia Zhang, Qiong Zhang, Jiaping Zhang#, Yuesheng Huang#. Hypoxia regulates CD9-mediated keratinocyte migration xia the P38/MAPK pathway. Sci. Rep.,2014; 4, 6304.
36 J Hu , Z Chu , J Han , Q Zhang , D Zhang , Y Dang , J Ren , HC Chan , J Zhang#, Y Huang#. Phosphorylation-dependent mitochondrial translocation ofMAP4 is an early step in hypoxia-induced apoptosis in cardiomyocytes. Cell Death Dis, 2014, 5, e1424.
37 Xue Xu , Qiong Zhang , Jiong-yu Hu, Dong-xia Zhang, Xu-pin Jiang , jie-zhi Jia , Jing-ci Zhu#, Yue-sheng Huang#. Phosphorylation of DYNLT1 at Serine 82 Regulates MTs Stability and Mitochondrial Permeabilization in Hypoxia. Mol. Cells, 2013, 36（10）：322-332.
38 Dong-xia Zhang Hong Yan, Jiong-yu Hu, Jia-ping Zhang, Miao Teng, Da-li Tong, Fei Xiang, Qiong Zhang, Ya-dong Fang, Guang-ping Liang, Yue-sheng Huang*. Identification of mitochondria translation elongation factor Tu as a contributor to oxidative damage of postburn myocardium. J Proteomics, 2012; 77（9）：469-479.
39 Jiaping Zhang，Jianda Dong，Hua Gu，Sidney Yu，Xiaohu Zhang，Yulin Gou，Wenming Xu，Andrew Burd，Lin Huang，Kenji Miyado，Yuesheng Huang#, Hsiao Chang Chan#. CD9 Is Critical for Cutaneous Wound Healing through JNK Signaling. Journal of Investigative Dermatology 2012；132：226–236.
40 Miao Teng, XiaoHui Zhao, YueSheng Huang*. Regenerating cardiac cells: insights from the bench and the clinic. Cell Tissue Res 2012；350: 189–197.
41 Hong Yan, Dong-Xia Zhang, Xiaohua Shi, Qiong Zhang, Yue-sheng Huang*. Activation of the Prolyl-hydroxylase oxygen-sensing signal cascade leads to AMPK activation in cardiomyocytes. J Cell Mol Med. 2012；16（9）：2049-2059
42 Xiao Rong, Ze-Yuan Lei, MD, Yong-Ming Dang, Huang Yue-sheng*. Prompt Myocardial Damage Initiates Hepatic, Renal and Intestinal Injuries Early Following Severe Burns in Rats. J Trauma, 2011, 71: 663–672.
43 Jiong-Yu Hu, Zhi-Gang Chu, Jian Han, Hong Yan, Yong-ming Dang, Qiong Zhang, Yue-Sheng Huang*. p38/MAPK Pathway Regulates Microtubule Polymerization Through Phosphorylation of MAP4 and Op18 in hypoxic cells. Cell. Mol. Life Sci., 2010, 67(2):321–333.
44 Fei Xiang, Yue-Sheng Huang*, Xiao-Hua Shi and Qiong Zhang. Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating mitochondrial permeability transition pore opening. FEBS J, 2010, 277 (8) ：1929–1938.
45 Miao Teng, Yong-Ming Dang, Jia-ping Zhang, Qiong Zhang, Ya-dong Fang, Jun Ren, Yue-sheng Huang*. Microtubular stability affects cardiomyocyte glycolysis by HIF-1α expression and endonuclear aggregation during early stages of hypoxia. Am J Physiol Heart Circ Physiol, 2010, 298（6）：H1919-H1931.
主编专著、参编教材：
1 黄跃生，吕国忠，姜玉峰，主编.国家卫健委能力建设和继续教育中心创面修复科专科能力建设专用系列教材. 第三册. 创面修复科全科医师分册. 郑州：郑州大学出版社，2021.
2 程飚，黄跃生，付小兵，主编。光、电及磁在创面治疗中的应用.郑州：郑州大学出版社，2019.
3 黄跃生，主编。烧伤学名词. 全国科学技术名词审定委员会公布. 北京：科学出版社， 2019.
4 黄跃生，主编. 中华医学百科全书.烧伤外科学。北京：中国协和医科大学学出版社，2017.
5 黄跃生，粟永萍，周继红，主编. 特殊致伤原因战创伤.郑州：郑州大学出版社，2016.
6 黄跃生，等主编. 烧伤关键治疗技术及预防急救指南.北京：人民军医出版社，2015.
7 黄跃生，主编. 烧伤早期救治与康复治疗学.石家庄：河北科学技术出版社，2015.
8 黄跃生，主编. 实用烧伤临床治疗学.郑州:郑州大学出版社,2013.
9 黄跃生，主编. 烧伤外科学。第1版。北京：科学技术文献出版社，2010.
10 黄跃生，主编.烧伤科特色治疗技术.北京：科学技术文献出版社，2004.
11 黄跃生. 烧伤. 见：周总光，赵玉沛主编. 外科学（第2版）（高等学校“十四五”医学规划新形态教材-供临床、基础、预防、护理、口腔、检验、药学等专业用）. 北京：高等教育出版社， 2021.
12 黄跃生. 烧伤、冻伤. 见：陈孝平，汪建平，赵继宗，主编. 外科学（第9版），（国家卫健委“十三五”规划教材，全国高等学校教材，供基础、临床、预防、口腔专业用）.北京：人民卫生出版社，2018.
13 黄跃生.烧伤和冷伤. 见：陈孝平，主编. 外科学（全国高等医药院校8年制教材）.北京：人民卫生出版社，2005.
14 黄跃生.烧伤与冻伤. 见：周总光，赵玉沛，主编.外科学（普通高等教育“十一五”国家级规划教材，全国高等医药院校规划教材）.北京：高等教育出版社，2009.
15 黄跃生.烧伤和冻伤. 见：陈孝平，主编.外科学（第2版）.全国高等学校教材供8年制及7年制临床医学等专业用. 北京：人民卫生出版社，2010.
16 黄跃生.烧伤和冻伤. 见：陈孝平，汪建平主编.外科学（第八版）.全国高等学校教材供基础、临床、预防、口腔医学类专业用. 北京：人民卫生出版社，2013.
17 黄跃生.烧伤和冻伤.见：赵玉沛，陈孝平主编.外科学（第3版）.供8年制及7年制临床医学等专业用. 北京：人民卫生出版社，2015.
18 黄跃生. 烧伤和冷伤.见：陈孝平，主编。外科学（全国高等医药院校7年制教材）。北京：人民卫生出版社，2002.