师资
个人简介
赵健,南方科技大学公共卫生及应急管理学院助理教授、副研究员、博士生导师。主要研究方向包括:(1)基于大规模队列研究探究生命早期暴露对全生命周期健康的影响;(2)分子流行病学研究中多组学大数据的因果推断和整合分析;(3)复杂疾病的药物新靶点发现。主持国家自然科学基金面上项目、中英国际合作项目(英方PI)和上海交通大学卓越公共卫生人才培养等项目,并作为研究骨干参与欧洲研究委员会(ERC)、英国国立卫生研究院(NIHR)、David Telling Charitable Trust资助项目和上海市科委重点项目。
截至目前,共发表SCI学术论文36篇,其中包括以第一或者通讯作者身份发表在Journal of Hepatology, Lancet-eBioMedicine, BMC Medicine, JCEM, Computer Methods and Programs in Biomedicine等领域内权威期刊,并担任BMC Medicine编委及包括Journal of Hepatology、Diabetes Care、International Journal of Epidemiology、Fertility and Sterility、Seminars in Liver Disease、Computers in Biology and Medicine等多个领域内权威SCI学术期刊的审稿人和review editor。
研究方向
1. 基于大规模队列研究探究生命早期暴露对全生命周期健康的影响
2. 分子流行病学研究中多组学大数据的因果推断和整合分析
3. 复杂疾病的药物新靶点发现
教育经历
2014-2019 澳大利亚科廷大学公共卫生学院,博士
2011-2014 四川大学华西公共卫生学院,硕士
2006-2011 安徽医科大学卫生管理学院,学士
工作经历
2023.12–至今,南方科技大学公共卫生及应急管理学院,助理教授、副研究员、博士生导师
2021-2023,上海交通大学医学院附属新华医院/公共卫生学院(兼聘),青年PI
2018-2020,英国布里斯托大学MRC-Integrative Epidemiology Unit,Senior Research Associate
科研项目
1. 国家自然科学基金面上项目:GLS2调控的谷氨酰胺代谢影响儿童非酒精性脂肪肝发病风险的出生队列及机制研究(2024年1月–2027年12月)
2. 国际科技合作项目:Children and adolescents' mental health and association with sleep pattern during the COVID-19 pandemic
代表性论文(#共同一作,*通讯作者)
1. Peng Q, Qiu W, Li Z, Zhao J*, Zhu C*. Fetal genetically determined birth weight plays a causal role in earlier puberty timing: evidence from human genetic studies. Human Reproduction. 2024 (in press) (中科院1区, IF = 6.1)
2. Zhao J*, Zeng J, Zhu C, Li X, Liu D, Zhang J, Li F, Targher G, Fan JG*. Genetically predicted plasma levels of amino acids and metabolic dysfunction-associated fatty liver disease risk: a Mendelian randomization study. BMC Medicine. 2023 Dec;21(1):1-2. (中科院1区, IF = 11.15)
3. Zhao J*, Stewart ID, Baird D, Mason D, Wright J, Zheng J, Gaunt TR, Evans DM, Freathy RM, Langenberg C, Warrington NM. Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study. EBioMedicine. 2023 Feb 1;88. (中科院1区, IF = 11.205)
4. Liu D, Gao X, Pan XF, Zhou T, Zhu C, Li F, Fan JG, Targher G, Zhao J*. The hepato-ovarian axis: genetic evidence for a causal association between non-alcoholic fatty liver disease and polycystic ovary syndrome. BMC Medicine. 2023 Feb 20;21(1):62. (中科院1区, IF = 11.15)
5. Liu D, Zhang Q, Bai P, Zhao J*. Assessing causal relationships between COVID-19 and non-alcoholic fatty liver disease, Journal of Hepatology, 2022 Mar 1;76(3):740-2. (中科院1区, IF=30.083)
6. Zeng J, Jin Q, Yang J, Yang RX, Zhang RN, Zhao J*, Fan JG*. Prevalence and incidence of MAFLD and associated anthropometric parameters among prepubertal children of the Shanghai Birth Cohort. Hepatology International. 2023 Sep 20:1-3. (JCR Q1, IF = 6.6)
7. Gan Y, Lu D, Yan C*, Zhang J*, Zhao J*. Maternal polycystic ovary syndrome and offspring birth weight: a Mendelian randomization study, The Journal of Clinical Endocrinology & Metabolism, 2021 Nov 24. (JCR Q1, IF= 6.134)
8. Zhao J, Xu J, He Y, Xiang M, Children and adolescents’ sleep patterns and their associations with mental health during the COVID-19 pandemic in Shanghai, China, Journal of Affective Disorders, 2022 Mar 15; 301: 337-344. (JCR Q1, IF= 6.533)
9. Zhao J, Zhao Y, Xiang L, Khanal V, Binns CW, Lee AH. A two-part mixed-effects model for analyzing clustered time-to-event data with clumping at zero. Computer Methods and Programs in Biomedicine. 2020 Apr 1;187:105196. (JCR Q1, IF=7.639)
10. Zeng X, Chen T, Cui Y, Zhao J, Chen Q, Yu Z, Zhang Y, Han L, Chen Y, Zhang J. In utero exposure to perfluoroalkyl substances and early childhood BMI trajectories: A mediation analysis with neonatal metabolic profiles. Science of The Total Environment. 2023 Apr 1;867:161504. (JCR Q1, IF = 10.75)