Self-introduction

Dr. Jinsong Bian is a Chair Professor and acting chair in the Department of Pharmacology, School of Medicine, Southern University of Science and Technology (SUSTech). Before joining in SUSTech, Dr. Bian was first appointed as an assistant professor (2003-2008) and then an Associate Professor with tenure (2009-2020) in the department of Pharmacology, Yong Loo Ling School of Medicine, National University of Singapore, Singapore. He also served as the deputy director of Drug Development Unit of National University of Singapore (NUS) and the Research Director of Department of Pharmacologoy, Yong Loo Lin School of Medicine, NUS in the period of 2016-2020.

Dr Bian earned his PhD degree from the University of Hong Kong and was awarded with the Dr KP Stephen Chang Gold Medal for the outstanding performance in the degree of Doctor of Philosophy in 2000.  Dr Bian then went on to complete his post-doctoral training under an American Heart Association Fellowship at the Albert Einstein College of Medicine in New York, USA in 2003.

Dr Bian is an Associate Editor, lead guest editor and reviewing editor of 13 international journals, including Antioxidant Redox Signalling, Journal of Alzheimer’s Disease, Frontiers in Pharmacology. He has served as a panel member of the Singapore National Medical Research Council (since 2007) and is also a consultant Member of the Greece Society of Studying Cardiovascular Diseases (SOS-CVD) (since 2010). He serves as an advisory committee member of different societies or conferences, including the International and European Conferences on the Biology of Hydrogen Sulphide, and the Asian Society for Vascular Biology (ASVB). He has published over 140 papers in international journals including Cir Res， Science Advances, PNAS, JASN, Redox Biology, and has delivered over 70 lectures at the invitation of international and regional scientific societies, institutes and conference organizers. He has received 14488 citations （Google scholar） and his H-index is 65 （Google scholar）.

Research Interests

Therapeutic target for pulmonary hypertension; 2. Novel functions of Na⁺/K⁺ ATPase; 3. Biology of endogenous mediators (e.g. hydrogen sulfide).

Educational background

1997-2000:     Ph. D.       Physiology, the University of Hong Kong.

1990-1993:     M. Sci.     Pharmacology, Nanjing Medical University, P. R. China.

1985-1990:     MBBS      Medicine, Xuzhou Medical University, P. R. China.

Professional experience

2025.06-present: Chair Professor in Department of Pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen, China

2020.05-2025.05: Professor in Department of Pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen, China

2009.01-2020.04: Associate Professor (with Tenure), Department of Pharmacology, Yong Loo Lin school of Medicine, National University of Singapore

2003.10-2008.12: Assistant Professor in Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

2000.05-2003.09: Research Associate and AHA fellow in Section of Molecular Cardiology and Department of Molecular Pharmacology, Albert Einstein College of Medicine, USA

1993.07-1997.03: Assistant Professor and lecturer in Department of Pharmacology, School of Basic Medical Science, Nanjing Medical University, China

Honors & Awards

2017   Research Excellence Award (AY2015/2016), Yong Loo Lin School of Medicine, National university of Singapore

2001   AHA fellowship, American Heart Association, New York affiliate

2000   Dr. KP Stephen Chang Gold Medal, the University of Hong Kong

2000   Mary Sun Scholarship 1999/2000, the University of Hong Kong

1999   Wong Ching Yee Medical Postgraduate Scholarship, the University of Hong Kong

1999   Prof. A.C. Brown Prize, the 7th Physiology Annual Meeting

1998   Certificate of Merit, the University of Hong Kong.

Professional Activities

2010-present:   Review Editor & Editorial Board Member, Frontiers in Pharmacology

2010-Present:   Review Editor and Editorial Board Member: Frontiers in Clinical and Translational Physiology

2011-present:   Editorial board member, Journal of Pharmacological Sciences

2015-2016:       Reviewing Editor, Antioxidant Redox Signalling

2015-2016:       Lead guest editor, Oxidative Medicine and Cellular Longevity

2010-2011:       Associate Editorship, Journal of Alzheimer’s Disease

2010-2012:       Editorial Board Member, Biomed Central-Medical Gas Research

2009-present:   Editorial Board Member, World Journal of Cardiology

2010-present:   Lead guest editor, Journal Biochemistry Research International

2011-present:   Editorial board member: World Journal of Hypertension

2010-present:   Editorial Board Member, Journal of Geriatric Cardiology

2013-2018:       Editor Board Member, Journal of Zhongshan University

Selected publications since 2020

1. Huang S, Dong W, Lin X, Xu K, Li K, Xiong S, Wang Z, Nie X #, Bian JS#. Disruption of the Na+/K+-ATPase/P2X7R complex in the microglia contributes to stress-induced anxiety. Immunity, 2024, 57, 495–512. [Impact factor: 25.5]

2. Bian JS, Chen J, Zhang J, Tan J, Chen Y, Yang X, Li Y, Deng L, Chen R, Nie X#. ErbB3 governs endothelial dysfunction in hypoxia-induced pulmonary hypertension. Circulation. 2024 Nov 5;150(19):1533-1553. [Impact factor: 35.5]

3. Zhang J*, Li Y*, Chen Y*, Zhang J, Jia Z, He M, Liao X, He S, Bian JS#, Nie XW#. o(8)G Site-Specifically Modified tRF-1-AspGTC: A Novel Therapeutic Target and Biomarker for Pulmonary Hypertension. Circ Res. 2024 Jun 21;135(1):76-92. [Impact factor: 16.5]

4. Sun HJ, Lu QB, Zhu XX, NI ZR, Su JB, Fu X, Chen G, Zheng GL, Nie XW, Bian JS# Pharmacology of hydrogen sulfide and its donors in cardiometabolic diseases. Pharmacological Reviews，2024 Aug 15;76(5):846-895. [Impact factor: 21.1]

5. Zhang J, Li Y, Zhang J, Liu L, Chen Y, Yang X, Liao X, He M, Jia Z, Fan J, Bian JS#, Nie X#. ADAR1 regulates vascular remodeling in hypoxic pulmonary hypertension through N1-methyladenosine modification of circCDK17. Acta Pharm Sin B. 2023 Dec;13(12):4840-4855 [Impact factor: 14.7]

6. Sun H, Xiong S, Cao X, Cao L, Zhu M, Wu Z, Bian JS#. Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65NF-κB and STST3. Redox Biology. 2021 Jan;38:101813. doi: 10.1016/j.redox.2020.101813. [Impact factor: 10.7]

7. Cao L, Xiong S, Wu Z, Ding L, Zhou Y, Sun H, Zhu M, Lee WT, Nie X#, Bian JS#. Anti-Na+/K+-ATPase immunotherapy ameliorates α-synuclein pathology through activation of Na+/K+-ATPase α1-dependent autophagy. Science Advances. 2021 Jan 27;7(5):eabc5062. doi: 10.1126/sciadv.abc5062. [Impact factor: 11.7]

8. Nie X#, Shen C, Tan J, Wu Z, Wang W, Chen Y ,Dai Y, Yang X,  Ye S, Chen J#, Bian JS#. Periostin: A Potential Therapeutic Target For Pulmonary Hypertension? Circulation Research. 2020 Oct 9;127(9):1138-1152. [Impact factor: 16.5]

9. Zhu M, Cao L, Xiong S, Sun H, Wu Z, Bian JS#. Na+/K+-ATPase-dependent autophagy protects brain against ischemic injury. Signal Transduction and Targeted Therapy. 2020 May 20;5(1):55. doi: 10.1038/s41392-020-0153-7. [Impact factor: 40.8]

10. Sun HJ, Xiong SP, Wu ZY, Cao L, Zhu MY, Moore PK, Bian JS#. Induction of caveolin 3/eNOS complex by nitroxyl (HNO) ameliorates diabetic cardiomyopathy. Redox Biol. 2020 May;32:101493. doi: 10.1016/j.redox.2020.101493. [Impact factor: 10.7]