Faculty
Educational background:
09/2019 – 06/2023 Ph.D. in Science, Southern University of Science and Technology (Supervisor: Prof. Xumu Zhang)
09/2016 – 06/2019 M.S. in Science, Wuhan University (Supervisor: Prof. Xumu Zhang)
09/2012 – 06/2016 B.S., Ningxia University
Work experience:
12/2025 – Present Research Assistant Professor, Southern University of Science and Technology
07/2023 – 12/2025 Associate Professor (University-appointed), China Three Gorges University
Honors and awards:
2020 Guangdong Provincial Outstanding Graduate Student
2019 Outstanding Graduate, Wuhan University
2018 National Scholarship for Master’s Students
Research Area:
Design and Synthesis of Novel Chiral Ligands and Their Applications in Asymmetric Hydrogenation
Publications:
1. Yin, C.*#; Wang, Z.#; Liang, Y.; Deng, J.; Zheng, Y.; Liu, Q.; Zeng, J.*; Zhang, X.*; Zhou, H.*,Nickel-Catalyzed Asymmetric Hydrogenation of All-Carbon Tetrasubstituted Alkenes Enabled by van der Waals Interactions. Angew. Chem. Int. Ed. 2025, Accepted.
2. Sun, H.; Ruan, S.; Ratovelomanana-Vidal, V.; Chen, G.-Q.*; Yin, C.*; Zhang, X.*, Amine−Borane-Promoted Rhodium-Catalyzed Asymmetric Transfer Hydrogenation of β‑Chloro Ketones. Org. Lett. 2025, 27, 11764.
3. Liu, Y.; Yang, C.; Zuo, L.; Liu, Q.; Zhang, X.; Hou, C.*; Yin, C.*; Zhou, H.*, Stereoselective Nickel-Catalyzed Iterative 1,2-Reduction of Trisubstituted Enones to Cycloalkanols Bearing Two Contiguous Stereocenters. Org. Lett. 2025, 27, 4183.
4. Chang, K.; Yang, L.; Liu, Y.; Cao, J.; Liu, Q.; Zuo, L.; Zhang, X.*; Yin, C.*; Zhou, H.*, Iridium-Catalyzed Chemo- and Enantioselective Hydrogenation of Cycloalkenones to Access Chiral Cycloallylalcohols. Org. Lett. 2024, 26, 9841.
5. You, Y.#; Yin, C.#; Xu, L.; Chen, G.-Q.; Zhang, X. Ate complexes in organic synthesis: from ate reagents to ate catalysts. Green Synth. Catal. 2024, 5, 141.
6. Chang, K.; Chou, R.; Yu, P.; Zuo, L.; Liu, Q.; Zhang, X.*; Yin, C.*; Zhou, H.*, Rhodium‐Catalyzed Asymmetric Transfer Hydrogenation of Aryl Ketones Involving Free Phenolic Hydroxyl Group(s). Chem. Eur. J. 2024, 10.1002/chem.202403055.
7. Yu, P.; Liu, Q.; Zuo, L.; Zhang, X.*; Yin, C.*; Zhou, H.*, Water-mediated one-pot multi-step synthesis of chiral 1,3-diarylpropan-1-ols by asymmetric hydrofunctionalisation of simple alkynes. Green Chem. 2024, 26, 4074.
8. Yin, C.; Zhang, R.; Pan, Y.; Gao, S,; Ding, X.; Bai, S.-T.; Lang, Q.; Zhang, X., PPM Ir-f-phamidol Catalyzed Asymmetric Hydrogenation of γ-Amino Ketones Followed by Stereoselective Cyclization for Construction of Valuable Chiral 2-Aryl-pyrrolidine Pharmacophores. J. Org. Chem. 2024, 89, 527.
9. Yin, C.#; Jiang, Y.-F.#; Huang, F.; Xu, C.-Q.; Pan, Y.; Gao, S,; Chen, G.-Q.; Ding, X.; Bai, S.-T.; Lang, Q.; Li, J.; Zhang, X., A 13-Million Turnover-Number Anionic Ir-Catalyst for a Selective Industrial Route to Chiral Nicotine. Nat. Commun. 2023, 14, 3718.
10. Yin, C.#; Pan, Y.#; Zhang, X.; Yin, Q., Catalytic Asymmetric Hydrogenation of Tetrasubstituted Unsaturated Lactams: An Efficient Approach to Enantioenriched 3,4-Disubstituted Piperidines. Org. Lett. 2022, 24, 675.
11. Liu, G.#; Yin, C.#; Yang, X.; Li, A.; Wang, M.; Zhang, X.; Dong, X., Highly Chemo- and Enantioselective Rh- Catalyzed Hydrogenation of beta-Sulfonyl-alpha,beta-unsaturated Ketones: Access to Chiral gamma- Ketosulfones. Org. Lett. 2021, 23, 19.
12. Yin, C.#; Pan, Y.#; Zheng, L.; Lin, B.; Wen, J.; Zhang, X., Iridium-catalyzed asymmetric hydrogenation of N- phosphinoylimine. Org. Chem. Front. 2021, 8, 1223.
13. Yin, C.#; Yang, T.#; Pan, Y.; Wen, J.; Zhang, X., Rh-Catalyzed Asymmetric Hydrogenation of Unsaturated Medium Ring NH Lactams: Highly Enantioselective Synthesis of N-Unprotected 2,3-Dihydro-1,5- benzothiazepinones. Org. Lett. 2020, 22, 920.
14. Tao, L.#; Yin, C.#; Dong, X.; Zhang, X., Efficient synthesis of chiral β-hydroxy sulfones via iridium- catalyzed hydrogenation. Org. Biomol. Chem. 2019, 17, 785.
15. Yin, C.; Dong, X.; Zhang, X., Iridium/f-Amphol-catalyzed Efficient Asymmetric Hydrogenation of Benzo- fused Cyclic Ketones. Adv. Synth. Catal. 2018, 360, 4319. (VIP)
16. Yin, C.#; Wu, W.#; Hu, Y.; Tan, X.; You, C.; Liu, Y.; Chen, Z.; Dong, X.; Zhang, X., Iridium-Catalyzed Asymmetric Hydrogenation of Halogenated Ketones for the Efficient Construction of Chiral Halohydrins. Adv. Synth. Catal. 2018, 360, 2119. (VIP)



