Educational background:
2014.09—2019.12 City University of Hong Kong, Doctor of Philosophy
2011.09—2014.07 Chengdu Institute of Organic Chemistry—CAS, Master of Organic Chemistry
2007.09—2011.07 Jilin Univesity, Bachelor of Chemistry
Work experience:
2024.08—Now SUSTech, Research Assistant Professor
2021.09—2024.07 Shenzhen Bay Laboratory, Assistant Researcher
2020.01—2021.07 University of Arizona, Postdoctoral Associate
Research Area：
Organic Chemistry, Coordination Chemistry, and Medicinal Chemistry
Publications：
1. Xu, Zoufeng†; Sung, Y.†; Tomat, E., Design of tetrazolium cations for the release of antiproliferative formazan chelators in mammalian cells. Journal of the American Chemical Society, 2023, 145, 15197-15206. https://doi.org/10.1021/jacs.3c02033
2. Xu, Zoufeng†; Lin L.†; Fu B.; Huang F.; Zhou Q.; Zhu G.; Wang, Z., Ligand substitution reactions afford oxaliplatin-based platinum(IV) complexes bearing axial alkoxido ligands. Inorganic Chemistry Frontiers, 2023. 10, 6058-6066. https://doi.org/10.1039/D3QI01562A
3. Xu, Zoufeng; Wang, Z.; Deng, Z.; Zhu, G., Recent advances in the synthesis, stability, and activation of platinum(IV) anticancer prodrugs. Coordination Chemistry Reviews, 2021, 442, 213991. https://doi.org/10.1016/j.ccr.2021.213991
4. Xu, Zoufeng; Tang, W. K.; Zhou, Q.; Chen, S.; Siu, C.-K.; Zhu, G., On the hydrolytic stability of unsymmetric platinum(IV) anticancer prodrugs containing axial halogens. Inorganic Chemistry Frontiers, 2021, 8, 3794-3802. https://doi.org/10.1039/D1QI00208B
5. Xu, Zoufeng†; Li, C.†; Zhou, Q.; Deng, Z.; Tong, Z.; Tse, M.-K.; Zhu, G., Synthesis, cytotoxicity, and mechanistic investigation of platinum(IV) anticancer complexes conjugated with poly(ADP-ribose) polymerase inhibitors. Inorganic Chemistry, 2019, 58, 16279-16291. https://doi.org/10.1021/acs.inorgchem.9b02839
6. Xu, Zoufeng; Chan, H. M.; Li, C.; Wang, Z.; Tse, M.-K.; Tong, Z.; Zhu, G., Synthesis, structure, and cytotoxicity of oxaliplatin-based platinum(IV) anticancer prodrugs bearing one axial fluoride. Inorganic Chemistry, 2018, 57, 8227-8235. https://doi.org/10.1021/acs.inorgchem.8b00706
7. Xu, Zoufeng; Li, C.; Tong, Z.; Ma, L.; Tse, M.-K.; Zhu, G., Halogenated PtIV complexes from N-halosuccinimide oxidation of PtII antitumor drugs: synthesis, mechanistic investigation, and cytotoxicity. European Journal of Inorganic Chemistry, 2017, 2017, 1706-1712. https://doi.org/10.1002/ejic.201601130
8. Xu, Zoufeng; Wang, Z.; Yiu, S.-M.; Zhu, G., Mono- and di-bromo platinum(iv) prodrugs via oxidative bromination: synthesis, characterization, and cytotoxicity. Dalton Transactions, 2015, 44, 19918-19926. https://doi.org/10.1039/C5DT03101J
Patent：
1. Tomat E., Xu Zoufeng, and Sung Y.-S., (2024) Tetrazolium and formazan compounds and methods of making and using the same. Patent No.: WO2024035831A1
2. Zhu G., Xu Zoufeng, and Zhou Q., (2024) Platinum complex, its preparation and therapeutic use. Patent No.: US20210371441A1
3.Zhu G., Wang Z., and Xu Zoufeng, (2021) Platinum complex, its preparation and therapeutic use. Patent No.: US10899781B2
4. Xun X., Ge G., Xu Zoufeng (2015) A synthetic method for cis-2-fluorocyclopropylamine. CN Patent, CN
106146319 A
