Research Interest

Yiming Li is an associate professor in the department of Biomedical Engineering at Southern University of Science and Technology. He received his B. Eng. in Biomedical Engineering at Shanghai Jiao Tong university in 2009, his master in Medical Physics at Heidelberg University in 2010, and his PhD in Biophysics at Karlsruhe Institute of Technology in 2015, under the supervision of Prof. Ulrich Nienhaus. Afterwards, he was an EMBL- EIPOD postdoctoral fellow at European Molecular Biology Laboratory (EMBL, Heidelberg) and a visiting scholar at Yale University (2016-2019). He has published many papers in high-impact international scientific journals, including Nature Methods, Nature Communications. The software he developed earned the first place in the SMLM challenge 2016, the most prestigious software contest in the field. Yiming’s research interests include development of cutting-edge 3D super-resolution imaging techniques and their biological applications.

Lab website: https://li-lab-sustech.github.io/

Education
2010-2015 Ph. D., Biophysics, Karlsruhe Institute of Technology
2009-2010 M. Sc., Medical Physics, Heidelberg University
2005-2009 B.E., Biomedical Engineering, Shanghai Jiao Tong University

Employment

2019-present Department of Biomedical Engineering, Southern University of Science and Technology, Associate Professor

2016-2019 European Molecular Biology Laboratory, Heidelberg, Postdoc

2016.02-2016.09 Yale University，Visiting Scholar

Honors and Awards
2013 International Symposium on Biomedical Imaging Travel Grant
2010-2013 Karlsruhe school of optics and photonics fellowship
2016-2019 EIPOD-Marie Curie Postdoc Fellowship

Publications

1.Yiming Li, Yu-Le Wu, Philipp Hoess, Markus Mund, and Jonas Ries. Depth-dependent PSF calibration and aberration correction for 3D single-molecule localization. Biomed. Opt. Express, 6, 2708-2718, (2019)
2. Yiming Li, Markus Mund, Philipp Hoess, Joran Deschamps, Ulf Matti, Bianca Nijmeijer,Vilma Jimenez Sabinina, Jan Ellenberg, Ingmar Schoen, Jonas Ries. Real-time 3D single-molecule localization using experimental point spread functions. Nat. Methods, 15, 367-369, (2018)

3.Yiming Li, Li Shang, G. Ulrich Nienhaus. Super-resolution imaging-based single particle tracking reveals dynamics of nanoparticle internalization by live cells. Nanoscale, 8, 7423-7429, (2016)

4.Yuji Ishitsuka, Natasha Savage, Yiming Li, Anna Bergs, Nathalie Grün, Daria Kohler, Rebecca Donnelly, G. Ulrich Nienhaus, Reinhard Fischer, Norio Takeshita. Superresolution microscopy reveals a dynamic picture of cell polarity maintenance during directional growth. Science Advances, 1, e1500947 (2016)

5.Yiming Li, Yuji Ishitsuka, Per Niklas Hedde, and G. Ulrich Nienhaus. Fast and efficient molecule detection in localization-based super-resolution microscopy by parallel adaptive histogram equalization. ACS Nano 7, 5207–5214 (2013)

6.Shuo Chen, Xiaorui Feng, Yiming Li, Chuanqing Zhou, Peng Xi, Qiushi Ren. Software Controlling algorithms for the system performance optimization of confocal laser scanning microscope. Biomed. Signal Process Control 3, 223-228 (2010)

7.Thevathasan, J. V. et al.Nuclear pores as versatile reference standards for quantitative superresolution microscopy. Nat. Methods 16, 1045–1053 (2019).

8.Yongdeng Zhang, et al., Nanoscale subcellular architecture revealed by multicolor 3D salvaged fluorescence imaging. Nature Methods, Accepted.