Faculty

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JIANG Xingyu
Chair Professor
Department Head
jiang@sustech.edu.cn

Professor Xingyu Jiang received his Bachelor's degree in Chemistry from the University of Chicago in 1999 and his Ph.D. from Harvard University in 2004. In 2005, he began an independent career at the National Center for Nanoscience and Technology (Chinese Academy of Sciences). In 2018, he was appointed as a Chair Professor at the Southern University of Science and Technology. Professor Xingyu Jiang was awarded the National Science Fund for Distinguished Young Scholars in 2010. He was an Innovative Talent Scholar by the Ministry of Science and Technology, and serves as a Chief Scientist of the National Key Research and Development Plan of the Ministry of Science and Technology. He received a Scientific Exploration Award from the Tencent Foundation. He was elected as a fellow of the Royal Society of Chemistry (UK) and American Society for Medical and Biological Engineering. He has published more than 400 papers, has over 200 invention patents. His main research areas include microfluidic chips and nanomedicine.

 

Lab Link

https://faculty.sustech.edu.cn/jiang/

http://xingyujiang.com

 

Education

Postdoctoral Research, Harvard University (2004-2005)

Ph.D. in Chemistry, Harvard University (2004)

B.S. in Chemistry, the University of Chicago (1999).

 

Work experience

Southern University of Science and Technology, 2018-Present.

National Center for Nanoscience and Technology (Chinese Academy of Sciences), 2005-2018.

 

Research interests

Analytical Chemistry; Microfluidics; Nanomedicine.

 

Major Awards/Research Projects

Fellow of the American Institute for Medical and Biological Engineering, 2020.

Tencent "Science Exploration Award", 2019.

Chief Scientist, National Key Research and Development Program of the Ministry of Science and Technology, 2019.

Fellow of the Royal Society of Chemistry, 2016.

National Science Fund for Distinguished Young Scholars , 2010.

Young Investigator, Human Frontiers Science Foundation, 2007.

 

Representative paper

1.Weakly Ionized Gold Nanoparticles Amplify Immunoassays for Ultrasensitive Point-of-care Sensors, Jiangjiang Zhang, Fengli Chai, Jia’an Li, Saijie Wang, Shuailong Zhang, Fenggang Li, Axin Liang, Aiqin Luo, Dou Wang, and Xingyu Jiang, Science Advances, 10, eadn5698. (2024)

2.Liquid Metal–Polymer Conductor-Based Conformal Cyborg Devices, Jie Qi, Shuaijian Yang, Yizhou Jiang, Jinhao Cheng, Saijie Wang, Qingyan Rao, Jiang XY, Chemical Reviews, 124, 2081-2137, (2024)

3.Three-dimensional Liquid Metal-based Neuro-interfaces for Human Hippocampal Organoids, Wu Y, Cheng JH, Qi J, Hang C, Dong RH, Low BC, Yu H, Jiang XY, Nature Communications, 15, 4047, (2024)

4.Phenylboronic Acid-Modified Gold Nanoclusters as a Nanoantibiotic to Treat Vancomycin-Resistant Enterococcus faecalis-Caused Infections, Wang L, Zheng WF, Zhong LN, Yang JY, Chen Y, Hou QH, Yu PY, Jiang XY, ACS Nano, 17, 19685-19695. (2023)

5.Stretchable Surface Electromyography Electrode Array Patch for Tendon Location and Muscle Injury Prevention, Yang SJ, Cheng JH, Shang J, Hang C, Qi J, Zhong LN, Rao QY, He L, Liu CQ, Ding L, Zhang MM, Chakrabarty S, Jiang XY, Nature Communications, 14, 6494. (2023)

6.Multiplexed Discrimination of SARS-CoV-2 Variants Via Plasmonic-enhanced Fluorescence in a Portable and Automated Device, Liu Y, Yang Y, Wang D, Shao PL, Tang JH, He TZ, Zheng JT, Hu RB, Liu YY, Xu ZY, Niu D, Lv JH, Yang JK, Xiao HJ, Wu S, He S, Tang ZR, Liu Y, Tang MJ, Jiang XY, Yuan J, Dai HJ, Zhang B, Nature Biomedical Engineering, 7, 1636–1648. (2023)

7.Tuning Ligands Ratio Allows for Controlling Gold Nanocluster Conformation and Activating a Nonantimicrobial Thiol Fragrance for Effective Treatment of MRSA-induced Keratitis, Pang ZY, Ren N, Wu YJ, Qi J, Hu FP, Guo Y, Xie YZY, Zhou DJ, Jiang XY, Advanced Materials, 35, 2303562. (2023)

8.Multi-armed Antibiotics for Gram-positive Bacteria, Jia YX, Chen WW, Tang RB, Zhang JJ, Liu XY, Dong RH, Hu FP, Jiang XY, Cell Host & Microbe, 31, 1101-1110. (2023)

9.Multi‐Targeted Peptide‐Modified Gold Nanoclusters for Treating Solid Tumors in the Liver, Xiao F, Chen Y, Qi J, Yao QF, Xie JP,Jiang XY, Advanced Materials, 17(8), 7250-7256 (2023)

10.In Situ Reprogramming of Tumor-Associated Macrophages with Internally and Externally Engineered Exosomes, Zhang LM, Lin YS,  Li SP, Guan XL, Jiang XY, Angew Chem Int Ed, 62,  e202217089 (2023)

11.Deploying Gold Nanomaterials in Combating Multi-Drug-Resistant Bacteria, Zhao XH, Tang H, Jiang XY, ACS Nano, 16, 7, 10066-10087. (2022)

12.Boronic Acid-Decorated Multivariate Photosensitive Metal–Organic Frameworks for Combating Multi-Drug-Resistant Bacteria, Chen M, Zhang JJ, Qi J, Dong RH, Liu HM, Wu DC, Shao HW, Jiang XY, ACS Nano, 16, 5, 7732–7744 (2022)

13.Aminophenol-Modified Gold Nanoparticles Kill bacteria with Minimal Ototoxicity, Wang L, Zheng WF, Zhong LN, Yang YK, Li SX, Li QZ, Jiang XY, Chemical Communications, 58, 2842–2845. (2022)

14.Fluorescent and Antibacterial Aminobenzeneboronic Acid (ABA)-Modified Gold Nanoclusters for Self-Monitoring Residual Dosage and Smart Wound Care, Wang L, Hou QH, Zheng WF, Jiang XY, ACS Nano, 15, 11, 17885-17894. (2021)

15.Controlling the Pyridinium–zwitterionic Ligand Ratio on Atomically Precise Gold Nanoclusters Allowing for Eradicating Gram-positive Drug-resistant Bacteria and Retaining Biocompatibility, Pang ZY, Li QZ, Jia YX, Yan WX, Qi jie, Guo Y, Hu FP, Dejian Zhou, Jiang XY, Chemical Science, 12, 14871-14882. (2021)

16.Oral Administration of Starting Materials for in vivo Synthesis of Antibacterial Gold Nanoparticles for Curing Remote Infections, Wang L, Yang JC, Li SX, Li QZ, Liu SQ, Zheng WF, Jiang XY, Nano Letters, 21, 1124−1131. (2021)

17.A Soft, Absorbable Temporary Epicardial Pacing Wire, Hang C, Ding L, Cheng SH, Dong RH, Qi J, Liu XY, Liu Q, Zhang Y, Jiang XY , Advanced Materials, 2101447, (2021)

18.Digital Hybridization Human Papillomavirus Assay with Attomolar Sensitivity without Amplification, Mou L, Hong HH Xu XJ, Xia Y, Jiang XY, ACS Nano, 15, 8, 13077–13084. (2021)

19.Integrating Concentration Gradient Generator and Single-cell Trapper Array for High-throughput Screening Bioeffects of Nanomaterials,  Liu XY, Jia YX, Han ZW, Hou QH, Zhang W, Zheng WF, Jiang XY, Angew Chem Int Ed, 60,22,12319-12322.(2021) 

20.Reversing the Chirality of Surface Ligands Can Improve the Biosafety and Pharmacokinetics of Cationic Gold Nanoclusters, Tang H, Li QZ, Yan WX, Jiang XY, Angew Chem Int Ed, 60,25,13829-13834. (2021)

21. Multilayered Electronic Transfer Tattoo that Can Enable the Crease Amplification Effect, Tang LX, Shang J, Jiang XY, Science Advances., 2021, 7, eabe3778. (2021)

22.Activating Antibacterial Effect of 4,6-diamino-2-pyrimidinethiol-modified Gold Nanoparticles by Reducing their Sizes, Xie YZY, Yang JC, Zhang JJ, Zheng WF, Jiang XY, Angew Chem Int Ed, 59,52,23471-23475. (2020)

23. Electronic Blood Vessel, Cheng SY, Hang C, Ding L, Jia LJ, Tang LX, Mou L, Qi J, Dong RH, Zheng WF, Zhang Y, Jiang XY, Matter, 3, 1–21. (2020)

24.Rapid Fabrication of Self-healing, Conductive and Injectable Gel as Dressings for Healing Wounds in Stretchable Parts of the Body, Li SX, Wang L, Zheng WF, Yang G, Jiang XY, Advanced Functional Materials,30,31,2002370. (2020)

25.Construction of Dopamine-Releasing Gold Surfaces Mimicking Presynaptic Membrane by On-Chip Electrochemistry, Li J, Sun CL, An PR, Liu XY, Dong RH, Sun JH, Zhang XY, Xie YB, Qin CG, Zheng WF, Zhang HL, Jiang XY, J Am Chem Soc, 141, 8816-8824. (2019)

26.Barcoded Point-of-care Bioassays, Yang MZ, Liu Y, Jiang XY, Chemical Society Reviews, 48, 850-884. (2019)

27.Controllable Assembly of Enzymes for Multiplexed Lab-on-a-Chip Bioassays with Tunable Detection Range, Xianyu YL, Wu J, Chen Y, Zheng W, Xie M, Jiang XY, Angew Chem Int Ed, 130, 7625-7639. (2018)

28.Skiving Stacked Sheets of Paper into Test Paper for Rapid and Multiplexed Assay, Yang MZ, Zhang W, Yang JC, Hu BF, Cao FJ, Zheng WS, Chen YP, Jiang XY, Science Advances, 3, eaao4862. (2017)

29.Gold Nanoclusters-assisted Delivery of NGF siRNA for Effective Treatment of Pancreatic Cancer, Lei YF, Tang LX, Xie YZY, Xianyu YL, Zhang LM, Wang P, Hamada Y, Jiang K, Zheng WF, Jiang XY, Nature Communications, 8, 15130. (2017)

30.Tunable Rigidity of (Polymeric Core)-(Lipid Shell) Nanoparticles for Regulated Cellular Uptake, Sun JS, Zhang L, Wang JD, Feng Q, Liu DB, Yin QF, Xu DY, Wei YJ, Ding BQ, Shi XH, Jiang XY, Advanced Materials, 27(8), 1402-1407. (2015)

31.Synergy of Non-antibiotic Drugs and Pyrimidinethiol on Gold Nanoparticles Against Superbugs, Zhao YY, Chen ZL, Chen YF, Xu J, Li JH, Jiang XY, J Am Chem Soc, 135(35), 12940-12943. (2013)

32.Small Molecule-capped Gold Nanoparticles as Potent Antibacterial Agents that Target gram-Negative Bacteria, Zhao YY, Tian Y, Cui Y, Liu WW, Ma WS, Jiang XY, J Am Chem Soc, 132(35), 12349-12356. (2010)

33.Using Azobenzene-embedded Self-Assembled Monolayers to Photochemically Control Cell Adhesion Reversibly, Liu DB, Xie YY, Shao HW, Jiang XY, Angew Chem Int Ed, 48(24), 4406-4408. (2009)

34.Visual Detection of Copper(II) by Azide- and Alkyne-functionalized Gold Nanoparticles Using Click Chemistry, Zhou Y, Wang SX, Zhang K, Jiang XY, Angew Chem Int Ed, 47(39), 7454-7456. (2008)

35.Fabrication of Aligned Fibirous Arrays by Magnetic Electrospinning, Yang DY, Lu B, Zhao Y, Jiang XY, Advanced Materials, 19(21),3702-3706. (2007)