师资

李鹏飞
副教授(研究员)
行政副系主任
0755-88018319
lipf@sustech.edu.cn

李鹏飞,博士,副教授(研究员),深圳市海外高层次“孔雀计划”人才(B类)、深圳市“后备级”人才;中共南方科技大学委员会委员、中共南方科技大学理学院委员会委员、化学系党总支书记;深圳市南山区第四、五届政协委员。于2009年中国科学院大连化学物理研究所获有机化学博士学位,师从梁鑫淼研究员。2009-2011年先后在香港理工大学、香港浸会大学从事博士后研究工作,师从陈新滋院士。2012年起任南方科技大学化学系助理教授(副研究员),组建有机仿生催化课题组,独立开展研究工作。2019年8月晋升为长聘副教授。该课题组致力于:1)不对称催化研究领域:远程立体控制实现立体中心的高效构建,具体体现在新型有机催化剂的研发及应用、高附加值化学品的策略合成;2)化学生物学:多功能探针的研发,具体体现在蛋白标记技术、磷酸化蛋白标准品的开发等研究方向。至今在PNAS、Org. Lett. 等期刊上发表论文40余篇,曾主持国家自然科学基金委、深圳市科技创新委员会等多个项目。
工作及教育背景
2019.08-今            南方科技大学化学系,副教授(研究员)
2012.01-2019.07 南方科技大学化学系,助理教授(副研究员)
2011.07-2011.12 香港浸会大学创意研究院,博士后研究员
导师:陈新滋(Albert S C Chan)院士
2009.07-2011.07 香港理工大学应用生物及化学科技学系,助理研究员
导师:陈新滋(Albert S C Chan)院士
2006.09-2006.07 中国科学院大连化学物理研究所,有机化学 博士
导师:梁鑫淼 研究员
2003.09-2006.07 大连理工大学化工学院,应用化学 硕士
导师:李宗石 教授
1999.09-2003.07 青岛大学化工学院,化学工程与工艺 学士

所获荣誉
2019 南方科技大学“优秀党务工作者”
2018 南方科技大学“优秀员工”
2018 南方科技大学“优秀工会干部”
2018 南方科技大学“优秀青年科研奖”
2018 南方科技大学“五年服务奖”
2018 南方科技大学“优秀共产党员”
2017 南方科技大学 "优秀党务工作者"
2017 南方科技大学“招生工作先进个人”
2016 中共深圳市委教育工委系统“优秀党务工作者”
2016 南方科技大学树德书院“优秀导师”
2016 南方科技大学“优秀服务奖”
2016 深圳市南山区“领航人才B类”
2015 南方科技大学“招生工作先进个人”
2013 深圳市“孔雀计划B类”
2012 南方科技大学“优秀员工”

 

发表论文

  1. Hongtian Liu, Juewei Ning, Guangjie Song, Xiangzhong Sun, Fengyu Su,* Pengfei Li,* Yanqing Tian.* Tricolor dual sensor for ratiometrically analyzing potassium ions and dissolved oxygen. Spectrochim. Acta Part A: Mol. Biomol. Spectrosc., 2020, 232, 118155.
  2. Chen Zhang,† Yuyu Cheng,† Fushuai Li,† Yepeng Luan, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective regiodivergent C-H bond functionalization of 1-naphthols with 1-azadienes. Adv. Synth. Catal., 2020, 362, 1286–1291.
  3. Lili Zhang,† Yuzhe Han,† Anqi Huang, Pei Zhang, Pengfei Li,* Wenjun Li.* Organocatalytic remote stereocontrolled 1,8-additions of thiazolones to propargylic aza-p-quinone methides (†co-first author). Org. Lett., 201921, 7415–7419. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)
  4. Chen Zhang,† Xinye Shang,† Yuyu Cheng,† Fushuai Li, Hanhui Zhao, Pengfei Li,* Wenjun Li.* Enantioselective construction of 3-substituted 3-amino-2-oxindoles containing an N,N-ketal skeleton via organocatalyzed aza-addition of isatin imines (†co-first author). Org. Biomol. Chem., 2019, 17, 8374–8378.
  5. Yuyu Cheng, Zhiqiang Fang, Yanwen Jia, Zhongyue Lu, Wenjun Li,* Pengfei Li.* Organocatalytic enantioselective conjugate addition of 2-naphthols to ortho-hydroxyphenyl substituted para-quinone methides: access to unsymmetrical triarylmethanes. RSC Adv., 2019, 9, 24212–24217.
  6. Yipeng Luan,† Anqi Huang,† Yuyu Cheng, Xiaohong Liu, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective Michael addition of oxazolones to 2-enoylpyridine N-oxides for assembling of pyridine N-oxides featuring vicinal oxygen-containing tetrasubstituted stereocenters (†co-first author). Adv. Synth. Catal., 2019, 361, 4208–4214.
  7. Wei Lin, Xiao Lin, Yuyu Cheng, Xiaoyong Chang, San Zhou, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective direct vinylogous Michael addition of γ-substituted deconjugate butenolides to azadienes. Org. Chem. Front., 2019, 6, 2452–2456.
  8. Pei Zhang,† Qiuhong Huang,† Yuyu Cheng, Rongshi Li,* Pengfei Li,* Wenjun Li.* Remote stereo-controlled construction of vicinal axially chiral tetrasubstituted allenes and heteroatom-functionalized quaternary carbon stereocenters (†co-first author). Org. Lett., 2019, 21, 503–507. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)
  9. Pengfei Zhang, Xing Guo, Chang Liu, Wenjun Li,* Pengfei Li.* Enantioselective construction of pyridine N-oxides featuring 2,3-dihydrofuran motifs via phosphine catalyzed [4+1]-annulation of 2-enoylpyridine N-oxides with Morita-Baylis-Hillman carbonates. Org. Lett., 2019, 21, 152-155. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)
  10. Chenxiao Qian,† Pangmiaomiao Zhang,† Wenjun Li,* Pengfei Li.* Phosphine catalyzed enantioselective [1 + 4]-annulation of Morita-Baylis-Hillman carbonates with α,β-unsaturated imines (†co-first author). Asian J. Org. Chem., 2019, 8, 242–245. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)
  11. Wei Lin, Chen Zhang, Wen Xu, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Organocatalytic asymmetric Michael addition of rhodanines to azadienes for assembling of sulfur-containing tetrasubstituted carbon stereocenters. Adv. Synth. Catal., 2019, 361, 476–480.
  12. Tao Wang,† Pengfei Zhang,† Wenjun Li,* Pengfei Li.* Phosphine-mediated enantioselective [1+4]-annulation of Morita–Baylis–Hillman carbonates with 2-enoylpyridines (†co-first author). RSC Adv., 2018, 8, 41620–41623. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)
  13. Kun Liu, Xinye Shang, Yuyu Cheng, Xiaoyong Chang, Pengfei Li,* Wenjun Li.* Regioselective [3+2]-annulation of hydrazonyl chlorides with 1,3-dicarbonyl compounds for assembling of polysubstituted pyrazoles. Org. Biomol. Chem., 2018, 16, 7811–7814.
  14. Qiuhong Huang, Yuyu Cheng, Huijun Yuan, Xiaoyong Chang, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective Mannich-type addition of 5H-thiazol-4-ones to isatin-derived Imines: access to 3-substituted 3-amino-2-oxindoles featured by vicinal sulfur-containing tetrasubstituted stereocenters. Org. Chem. Front., 2018, 5, 3226–3230.
  15. Fei Qi, Fang Fang, Pengfei Li.* Catalyst-free phospha-nucleophilic substitution of hydroxylactams by diarylphosphine oxide. Current Organocatalysis, 2018, 5, 145–149.
  16. Bizhu Chu,† An He,† Yeteng Tian, Wan He, Peizhong Chen, Jintao Hu, Wenbin Zhou, Mingjie Zhang, Pengyuan Yang, Ying Sun,* Pengfei Li,* Tony Hunter, Ruijun Tian.* Photoaffinity engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples (†co-first author). Proc. Natl. Acad. Sci. USA, 2018, 115, E8863–E8872. (Highlighted by SUSTech News)
  17. Yuyu Cheng, Zhiqiang Fang, Wenjun Li,* Pengfei Li.* Phosphine-mediated enantioselective [4+1] annulations between ortho-quinone methides and Morita-Baylis-Hillman carbonates. Org. Chem. Front., 2018, 5, 2728–2733. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)
  18. Lili Zhang, Huijun Yuan, Wei Lin, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Catalyst-controlled diastereodivergent construction of vicinal sulfur-functionalized quaternary and tertiary stereocenters. Org. Lett., 2018, 20, 4970–4974.
  19. Qiuhong Huang, Lili Zhang, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Enantioselective construction of vicinal sulfur-containing tetrasubstituted stereocenters via organocatalyzed Mannich-type addition of rhodanines to isatin imines. Adv. Synth. Catal., 2018, 360, 3266–3270.
  20. Wenjun Li,* Xianhong Xu, Pengfei Zhang, Pengfei Li.* Recent advances in catalytic enantioselective reactions of para-quinone methides. Chem. Asian J., 2018, 13, 2350–2359. (Invited for the Special Issue on Homogeneous Catalysis from Young Investigators in Asia)
  21. Wenjun Li,* Huijun Yuan, Zhantao Liu, Zhongyin Zhang, Yuyu Cheng, Pengfei Li.* NHC-catalyzed enantioselective [4 + 3] cycloaddition of ortho-hydroxyphenyl substituted para-quinone methides with isatin-derived enals. Adv. Synth. Catal., 2018, 360, 2460–2464. (Highly Cited Paper, Web of Science, Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)
  22. Wenjun Li,* Xianhong Xu, Yang Liu, Hua Gao, Yuyu Cheng, Pengfei Li.* Enantioselective organocatalytic 1,6-addition of azlactones to para-quinone methides: an access to α,α-disubstituted and β,β-diaryl-α-amino acid esters. Org. Lett., 2018, 20, 1142–1145. (Highly Cited Paper, Web of Science, Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)
  23. Xinye Shang, Kun Liu, Zhongyin Zhang, Xianhong Xu, Pengfei Li,* Wenjun Li.* Direct access to spirobiisoxazoline via double 1,3-dipolar cycloaddition of nitrile oxide with allenoate. Org. Biomol. Chem., 2018, 16, 895–898.
  24. Yuzhe Han, Yingzu Zhu, Pangmiaomiao Zhang, Wenjun Li,* Pengfei Li.* A catalyst-free cycloaddition reaction: access to spiro[chroman-3,2’-indene-1’,3’-dione] scaffolds. Chemistryselect, 2017, 2, 11380–11383.
  25. Lili Zhang,† Xiao Zhou,† Pengfei Li, Zhantao Liu, Yang Liu, Yong Sun, Wenjun Li.* Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and β-functionalized ketone (†co-first author). RSC Adv., 2017,7, 39216–39220.
  26. Yuyu Cheng,† Yuzhe Han,† Pengfei Li.* Organocatalytic enantioselective [1+4] annulation of Morita-Baylis-Hillman carbonates with electron-deficient olefins: access to chiral 2,3-dihydrofuran derivatives (†co-first author). Org. Lett. 2017, 19, 4774–4777. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)
  27. Yuyu Cheng, Pengfei Zhang, Yanwen Jia, Zhiqiang Fang, Pengfei Li.* Organocatalytic condensation–ring opening–annulation cascade reactions between N-Bocindolin-2-ones/benzofuran-2(3H)-ones and salicylaldehydes for synthesis of 3-arylcoumarins. Org. Biomol. Chem., 2017, 15, 7505–7508. (Highlighted as Front Cover)
  28. Lu Yu, Yuyu Cheng, Fei Qi, Rou Li, Pengfei Li.* Organocatalytic regioselective, diastereoselective, and enantioselective annulation of cyclic 1-azadiene with γ-nitro ketone via 3,4-cyclization. Org. Chem. Front., 2017, 4, 1336–1340.
  29. Fei Qi, Rou Li, Fang Fang, Pengfei Li.* Autocatalytic nucleophilic substitution of hydroxylactam by thiophenol: access to N(acyl),S-acetals. Current Green Chemistry, 2016, 3, 235–241.
  30. Jindian Duan, Yuyu Cheng, Jing Cheng, Rou Li, Pengfei Li.* Organocatalytic asymmetric benzylation and aldol-hemiacetalization of α,β-unsaturated trifluoromethyl ketones: efficient enantioselective construction of 3,4-dihydroisocoumarins. Chem. Eur. J., 2017, 23, 519–523. (Highlighted asInside Front Cover)
  31. Jindian Duan, Yuyu Cheng, Rou Li, Pengfei Li.* Synthesis of spiro[indane- 1,3-dione-1-pyrrolines] via copper-catalyzed heteroannulation of ketoxime acetates with 2-arylideneindane-1,3-diones. Org. Chem. Front., 2016, 3, 1614–1618. (Highlighted as Inside Front Cover)
  32. Lu Yu, Yuyu Cheng, Rou Li, Yanhua Jiao,* Pengfei Li.* Tandem cyclization reaction between optically active γ-nitro ketone and chalcone towards the synthesis of chiral cyclohexane skeletons bearing five stereocenters. Chin. J. Org. Chem., 2016, 36, 1572–1579. (Highlighted as Front Cover)
  33. Jindian Duan, Jing Cheng, Yuyu Cheng, Pengfei Li.* Synthesis of dinitrogen-fused spiro heterocycles via organocatalytic 1,3-dipolar cycloaddition of 2-arylidene-1,3- indandiones and azomethine imines. Asian J. Org. Chem., 2016, 5, 477–480.
  34. Lu Yu, Zhen Yang, Jianzhao Peng, Pengfei Li.* Substrate-controlled synthesis of functionalized cyclohexanes with four stereocenters via organocatalytic asymmetric domino reaction between γ-nitro ketone and enone. Eur. J. Org. Chem., 2016, 535–540.
  35. Jindian Duan, Jing Cheng, Bing Li, Fei Qi, Pengfei Li.* Enantioselective synthesis of spiro [1,3-indanedione-tetrahydrothiophene]s by organocatalytic sulfa-Michael/Michael domino reaction. Eur. J. Org. Chem., 2015, 6130–6134.
  36. Jindian Duan, Jing Cheng, Pengfei Li.* Enantioselective construction of spiro-1,3-indandiones with three stereocenters via organocatalytic Michael-aldol reaction of 2-arylideneindane-1,3-diones and nitro aldehydes. Org. Chem. Front., 2015, 2, 1048–1052.
  37. Jindian Duan, Jing Cheng, Pengfei Li.* DBU catalyzed one-pot multicomponent reaction for the synthesis of spirocyclic tetrahydrothiophene derivatives. Current Organocatalysis, 2016, 3, 216–220.
  38. Fang Fang, Genghong Hua, Feng Shi,* Pengfei Li.* Organocatalytic enantioselective Friedel-Crafts reaction: an efficient access to chiral isoindolo-β-carboline derivatives. Org. Biomol. Chem., 2015, 13, 4395–4398. (Highlighted as Inside Front Cover)
  39. Hongqi Tao, Jindian Duan, Qijie He, Jun Wang,* Pengfei Li.* Organocatalytic efficient synthesis of 3-substituted-3-hydroxy-indolin-2-one derivatives from isatins and 4-phenylbut-3-yn-2-one. Scientia Sinica Chimica, 2015, 45(4), 391–395.
  40. Lu Yu, Qingjing Yang, Pengfei Li.* Phase-transfer-catalyst-mediated domino reaction of γ-nitro ketones with chalcones: approach to functionalized six-membered-ring carbocycles. Eur. J. Org. Chem., 2014, 7499–7504.
  41. Lu Yu, Pengfei Li.* New simple primary amine-thiourea organocatalysts and their application in asymmetric conjugate addition. Tetrahedron Lett., 2014, 55, 3697–3700.
  42. Hongqi Tao, Jindian Duan, Pengfei Li.* Inorganic-base-catalysed synthesis of α, β- unsaturated ketones and 3,5-disubstituted cyclohex-2-en-1-ones. Asian J. Org. Chem., 2014, 3, 644–648.
  43. Xin Yang, Jun Wang*, Pengfei Li.* Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons. Org. Biomol. Chem., 2014, 12, 2499–2513. (Highlighted as Front Cover)
  44. Pengfei Li,* Fang Fang, Ji Chen, Jun Wang.* Organocatalytic asymmetric aza-Michael addition of pyrazole to chalcone. Tetrahedron: Asymmetry, 2014, 25, 98–101.
  45. Jindian Duan, Pengfei Li.* Asymmetric organocatalysis mediated by primary amines derived from cinchona alkaloids: recent advances. Catal. Sci. Technol., 2014, 4, 311–320.
  46. Yinuo Wu, Fuk Yee Kwong, Pengfei Li,* Albert S C Chan.* An efficient oxidative cross-coupling reaction between C-H and N-H bonds; a transition-Metal-Free protocol at room temperature. Synlett, 2013, 24, 2009–2013.
  47. Jun Wang, Pengfei Li,* Pui Ying Choy, Albert S C Chan,* Fuk Yee Kwong.* Recent advances and applications in organocatalytic asymmetric aza-Michael      addition. ChemCatChem, 2012, 4, 917–925. (Invited, Highlighted as Back Cover)