李婷婷，南方科技大学生物医学工程系研究助理教授，2023年获得南方科技大学理学博士学位，主要研究方向为生物医学光学成像，致力于快速、大视场、高分辨率光声成像技术及以其为核心的多模态光学成像技术的研发，并将其广泛应用于生命科学领域的基础和前沿研究中。迄今为止，在Nature Communications, Laser & Photonics Reviews, Optics Letters, Advanced Functional Materials, Advanced Science, Biomedical Optics Express等国际期刊上共发表SCI论文24篇，其中一作及通讯作者论文11篇；申请或授权专利4项；主持国自然青年科学基金项目C类1项、深圳市优秀科技创新人才培养项目1项，作为核心成员或骨干参与国家自然科学基金重点项目、中华人民共和国科学技术部重点研发计划、深圳市基础研究重点项目、深圳市医学科学院前沿探索项目等7项。

教育背景

2019.09～2023.06  博士，  生物学，南方科技大学

2014.09～2017.06  硕士，  电子与通信工程，电子科技大学

2010.09～2014.06  学士，  电子信息科学与技术，河南科技大学

工作经历

2025.09～至今研究助理教授，南方科技大学

2023.07～2025.09    博士后， 物理学，南方科技大学

2018.04～2019.08    科研助理， 南方科技大学

2017.07～2018.03    软件工程师，珠海和佳医疗设备股份有限公司

奖励情况

1. 优秀研究生，南方科技大学，2023

2. 国家奖学金，南方科技大学，2022

3. 优秀学生报告奖，中国光学学会，2021

承担项目

1.国家自然科学基金委，青年科学基金项目C类，62505125，多自由度超快光声脑功能成像技术研究，2026.01-2028.12，30万元， 主持

2.深圳市科技创新委员会，优秀科技创新人才培养（博士基础研究启动），RCBS20231211090802011，基于光声扩展显微技术的亚细胞结构成像研究，2024.06-2026.06，30万元，主持

3.国家自然科学基金委，重点项目，62435008，多参量大视场快速光声子宫内窥体成像研究，2025.01-2029.12，231万元，参与

4.中华人民共和国科学技术部，重点研发计划，2024YFF0507200，光学多模态信息脑活体成像关键问题研究，2024.12-2029.12，1432.2万元，参与

5.中华人民共和国科学技术部，重点研发计划，2023YFF0715300，超分辨光声成像分析仪，2023.12-2026.11，600万元，参与

6.深圳市科技创新委员会，基础研究专项基础研究重点项目，JCYJ20241202124916023，新型快速全脑高分辨率成像技术和方法研究，2024.12-2027.12，200万元，参与

7.深圳市医学科学院，前沿探索一般项目，B2402046，基于光学影像技术的阿尔茨海默病伴神经血管偶联变化研究，2025.01-2027.12，300万元，参与

8.深圳市科技创新委员会，基础研究专项重点项目，20231116104616001，大视场光声内窥显微技术机理研究，2023.10-2026.09，100万元，参与

9.深圳市科技创新委员会，基础研究专项基础研究面上项目，JCYJ20220530114010023，人工超表面调控下的微波热声成像技术及其在乳腺癌早期诊断中的应用研究，2022.10-2025.10，30万元，参与

期刊论文（*通讯作者, #共同一作）

1. Wei Qin#, Tingting Li#, Linyang Li#, Tian Jin, Baochen Li, Weizhi Qi, Yifan Chen, Haoyang Li, Shijie Ruan, Heng Guo, Xiao Liang, Lei Xi*, A cortex-wide multimodal microscope for simultaneous Ca2+ and hemodynamic imaging in the awake mouse, Nature communications, Accepted.

2. Tingting Li#, Heng Guo#, Ye Liu#, Weizhi Qi, Changfeng Wu, Lei Xi*, All-in-One Photoacoustic Theranostics Using Multi-Functional Nanoparticles, Advanced Functional Materials, 2022, 32(6), 2107624.

3. Tingting Li#, Xinrui Gong#, Heng Guo, Lei Xi*, Photoacoustic expansion microscopy of melanosomes, Optics Letters, 2024, 49(4), 798-801.

4. Wei Qin#, Tingting Li#, Yifan Chen#, Xiao Liang, Linyang Li, Heng Guo, Weizhi Qi*, Lei Xi*, High-efficiency photoacoustic microscopy for ultrafast hemodynamic imaging, Laser & Photonics Reviews, 2025, 2401545, doi: 10.1002/lpor.202401545. Publish Online

5. Yuanlong Zhao, Tingting Li*, Heng Guo, Rui Hu, Lei Xi*, Long-term Assessment of Cutaneous Inflammation and Treatment using Optical Resolution Photoacoustic Microscopy, Biomedical Optics Express, 2023, 174(9), 4775-4789.

6. Jun Wang#, Tingting Li#, Jen-shyang Ni#, Heng Guo, Tianyi Kang, Zeshun Li, Menglei Zha, Songbo Lu, Chen Zhang, Weizhi Qi, Lei Xi*, Kai Li*, Photoacoustic Force-Guided Precise and Fast Delivery of Nanomedicine with Boosted Therapeutic Efficacy, Advanced Science, 2021, 8(16), 2100228.

7. Zeshun Li#, Tingting Li#, Chen Zhang#, Jen-shyang Ni, Yaoyao Ji, Aihui Sun, Dinglu Peng, Weijun Wu, Lei Xi*, Kai Li*, A multispectral Photoacoustic Tracking Strategy for Wide-field and Realtime Monitoring of Macrophages in Inflammation, Analytical Chemistry, 2021, 93(24), 8467-8475.

8. Weizhi Qi#, Tingting Li#, Chen Zhang#, Fei Liu, Jun Wang, Dandan Chen, Xiaofeng Fang, Changfeng Wu*, Kai Li*, Lei Xi*, Light-Controlled Precise Delivery of NIR-Responsive Semiconducting Polymer Nanoparticles with Promoted Vascular Permeability, Advanced Healthcare Materials, 2021, 10(9), 2100569.

9. Huilin Xie#, Chen Zhang#, Tingting Li#, Lianrui Hu, Jianquan Zhang, Heng Guo, Zhao Liu, Dinglu Peng, Zeshun Li, Weijun Wu, Ji Gao, Zhenyu Bi, Jinghan Wang, Pengfei Zhang, Ryan T. K. Kwok, Jacky W. Y. Lam, Zhihong Guo, Lei Xi*, Kai Li*, Ben Zhong Tang*, Fast Delivery of Multifunctional NIR-II Theranostic Nanoaggregates Enabled by the Photoinduced Thermoacoustic Process, Advanced Science, 2023, 10(19), 2301104.

10. Ziyi Xu#, Mingkun Lv#, Jingkai Yang#, Tingting Li#, Jiahui Lv, Jiaxin Li, Hongjun Xiao, Yicheng Yang, Siyu Zhou, Xuan Tan, Li Cheng, Heng Guo, Lei Xi*, Pan-Lin Shao*, Bo Zhang*, An efficient heat and peroxynitrite generating nanoplatform for multimodal imaging-guided precision tumor phototherapy, Aggregate, 2025, e70040, doi: 10.1002/agt2.70040. Publish Online

11. Lin Huang#, Tingting Li#, Huabei Jiang*, Technical Note: Thermoacoustic imaging of hemorrhagic stroke: A feasibility study with a human skull, Medical Physics, 2017, 44(4), 1494-1499.

12. Xiao Liang#, Yuanlong Zhao#, Linyang Li, Hongdian Sun, Wei Qin, Tingting Li , Heng Guo, Weizhi Qi, Lei Xi*, Non-telecentric photoacoustic microscopy for multi-scale imaging, Photoacoustics, 2025, 45, 100750.

13. Yujie Wang#, Linyang Li#, Weizhi Qi, Wei Qin, Tian Jin, Tingting Li, Pavel Subochev, Lei Xi*, Non-telecentric photoacoustic microscopy for multi-scale imaging, Optics Letters, 2024, 49(10), 2637-2640.

14. Linyang Li#, Wei Qin#, Tingting Li, Junning Zhang, Baochen Li, Lei Xi*, High-speed Adaptive Photoacoustic Microscopy, Photonics Research, 2023. 11(12), 2084-2092.

15. Qiang Liu, Xiao Liang, Tingting Li, Weian Chao, Weizhi Qi, Tian Jin, Yubin Gong, Huabei Jiang, Lei Xi*, Split ring resonator topology based microwave induced thermoacoustic imaging (SRR-MTAI), IEEE Transactions on Medical Imaging, 2023, 42(8), 3250647.

16. Heng Guo#, Qian Chen#, Tingting Li, Desheng Sun, Lei Xi*, Photoacoustic-triggered nanomedicine delivery to internal organs using a dual-wavelength laparoscope, Journal of Biophotonics, 2022, 15(9), e202200116.

17. Aihui Sun#, Yaoyao Ji#, Yaxi Li, Wenhui Xie, Zhihe Liu, Tingting Li, Tian Jin, Weizhi Qi, Kai Li, Changfeng Wu, Lei Xi*, Multi-color Photoacoustic volumetric imaging of subcellular structures, ACS Nano, 2022, 16(2), 3231-3238.

18. Yongchao Wang#, Ruoxi Zhang#, Qian Chen, Heng Guo, Xiao Liang, Tingting Li, Weizhi Qi, Lei Xi*, Visualization of blood-brain barrier disruption with dual-wavelength high-resolution photoacoustic microscopy, Biomedical Optics Express, 2022, 13(3), 1537-1550.

19. Xiaoxia Song, Rongxin Qian, Tingting Li, Wei Fu, Lijun Fang, Yuzhen Cai, Heng Guo, Lei Xi, U Kei Cheang*, Imaging-Guided Biomimetic M1 Macrophage Membrane-Camouflaged Magnetic Nanorobots for Photothermal Immunotargeting Cancer Therapy, ACS Applied Materials & Interfaces, 2022, 14(51), 56548-56559.

20. Aihui Sun, Tingting Li, Tian Jin, Yaxi Li, Kai Li, Chaolong Song, Lei Xi*, Acoustic Standing Wave Aided Multiparametric Photoacoustic Imaging Flow Cytometry, Analytical Chemistry, 2021, 93(44), 14820-14827.  

21. Tianyi Kang#, Jen-Shyang Ni#, Tingting Li, Jun Wang, Zeshun Li, Yaxi Li, Menglei Zha, Chen Zhang, Xue Wu, Heng Guo, Lei Xi, Kai Li*, Efficient and Precise Delivery of MicroRNA by Photoacoustic Force Generated from Semiconducting Polymer-Based Nanocarriers, Biomaterials, 2021, 275, 120907.

22. Yanan Gao, Zhihua Li, Yin Hong, Tingting Li, Xiaoyan Hu, Luyao Sun, Zhengchang Chen, Zijian Chen, Zhiheng Luo, Xin Wang, Jian Kong, Guanglei Li, Hsing-Lin Wang, Hwa Liang Leo, Hanry Yu, Lei Xi, Qiongyu Guo*, Decellularized liver as a translucent ex vivo model for vascular embolization evaluation, Biomaterials, 2020, 240, 119855.

23. Fei Liu#, Tian Jin#, Ruopeng Yan, Tingting Li, Biao Hu, Lei Yao, Tianye Huang, Chaolong Song*, Lei Xi*, An opto-acousto-fluidic microscopic system with a high spatiotemporal resolution for microfluidic applications, Optics Express, 2019, 27(2), 1425-1432.

24. Zhihui Chi, Yuan Zhao, Jinge Yang, Tingting Li, Guang Zhang, Huabei Jiang*, Thermoacoustic Tomography of In Vivo Human Finger Joints, IEEE Transactions on Biomedical Engineering, 2019, 66(6), 1598-1608.

学术会议

1. 李婷婷，齐伟智，吴长锋*，奚磊*，基于光声效应的药物递送和肿瘤诊疗研究，BPC 2022 (口头报告)

2. Tingting Li, Xinrui Gong, Weizhi Qi, Lei Xi*, Ultrafast Random-Access Scanning Photoacoustic Microscopy, PIBM 2021 (海报+口头报告)

3. 李婷婷，齐伟智，王俊，康天怿，吴长锋*，李凯*，奚磊*，基于光声精准递送纳米粒子的肿瘤诊疗，COS 2021 (海报)

申请专利

1. 奚磊，王永超，郭恒，张若曦，李婷婷，基于双波长光声显微成像的血脑屏障损伤评估装置及方法，ZL 202111083736.6，发明专利，中国，2023-09-01

2. 奚磊，李婷婷，郭恒，齐伟智，一种光声显微成像诊疗装置及其使用方法，202011615857.6，发明专利，中国，2020-12-30

3. 奚磊，李婷婷，齐伟智，一种基于随机访问扫描的光声显微成像装置及方法，202311350742.2，发明专利，中国，2023-10-18

4. 奚磊，王玉洁，李林阳，齐伟智，秦伟，李婷婷，基于无级调节中继光路的多尺度光声显微镜及其成像方法，202410208119.1，2024-02-26