基本概况：

张斌田，南方科技大学环境科学与工程学院副教授（研究员，博士生导师，独立PI）, 深圳市城市环境健康风险精准测量与预警技术重点实验室副主任。本科毕业于南开大学，博士毕业于中科院生态中心，先后在中科院福建物构所及美国亚利桑那州立大学从事研究工作，入选国家级海外青年人才及深圳市孔雀特聘岗位。主要研究方向为环境分析化学及生物传感技术，围绕新污染物的快速检测、污染物的毒性效应筛查以及分子毒理学研究，发展高灵敏的生物分析方法、生物传感器及便携式检测器件和设备等。主持国家自然科学基金面上等多项国家级和省市级项目。在Nature Commun、PNAS、JACS、ACS Nano、Nano Letters、ES&T、AC等国际知名学术期刊发表论文60余篇，申请及获批国际专利（PCT）、美国和中国专利12项，实现专利技术转让2项。曾获第一届“新污染物治理青年创新奖”、“亚利桑那州立大学技术转让优秀奖”、“ACS 特殊贡献奖”等奖励。担任SCI期刊Environ. Sci. Nano副主编、中国环境科学学会新污染物治理专业委员会委员。

工作经历：

2022 - 至今  南方科技大学  副教授（PI，研究员）

2021 - 2022  南方科技大学  助理教授（PI，副研究员）

2016 - 2021  亚利桑那州立大学  副研究员（合作导师：Stuart Lindsay教授）

2012 - 2016  中科院福建物质结构研究所  助理/副研究员（合作导师：林璋教授）

教育背景：

2007 - 2012  中科院生态环境研究中心，环境科学，博士学位（导师：郭良宏研究员）

2003 - 2007  南开大学，环境科学，学士学位 （导师：朱琳教授）

社会兼职：

1. RSC《Environmental Science: Nano》副主编

2. 中国环境科学学会新污染物治理专业委员会委员

3. 《Journal of Analysis and Testing》青年编委

获奖及荣誉：

1. 2026：南方科技大学“优秀新生班主任”

2. 2024：第一届“新污染物治理青年创新奖”

3. 2024：RSC“视觉科研”封面大赛优秀导师奖

4. 2021：ACS特殊贡献奖

5. 2020：《Sensors & Actuators: B. Chemical》优秀审稿人奖

6. 2019：ASU技术转让优秀奖

研究方向：

1. 新污染物的快速检测技术研发

2. 污染物毒性效应的筛查与检测

3. 电化学/光电化学传感器和微流控芯片

4. 原子力显微镜及扫描隧道显微镜的生物分析应用

5. 单分子电学检测技术研究

6. 新型生物传感器及便携式检测仪器研制

（欢迎具有环境科学、化学、材料等相关学科背景的同学报考硕士及博士研究生；课题组也长期招聘相关专业背景的博士后，一起合作探索有趣的研究课题！）

代表性科研项目：

1. 2026“基于单分子识别隧穿技术的DNA加合物结构识别与检测方法研究”，国家自然科学基金，面上项目（主持）

2. 2024 “深圳市多介质环境中典型新污染物的识别、暴露评估与健康风险管控”，深圳市科创委，深圳市高层次人才团队项目（核心成员）

3. 2023 “用于基因毒性标志物8-羟基鸟嘌呤检测的分子电导传感器研究”，深圳市科创委，稳定支持面上项目（主持）

4. 2023 “基于单分子蛋白电导的内分泌干扰物与蛋白相互作用研究”，国家自然科学基金，面上项目（主持）

5. 2023 “城市大气复合污染条件下神经退行性疾病的风险因子筛查控制技术研究与应用示范”，深圳市科创委，可持续发展科技专项（课题负责）

6. 2023 “深圳市城市环境健康风险精准测量与预警技术重点实验室”，深圳市科创委，重点实验室组建项目（学术带头人、副主任）

7. 2014 “基于分子印迹技术的光电化学传感器检测酚类内泌干扰物 ”，国家自然科学基金，青年项目（主持）

8. 2014 “基于ZnO纳米花的光电化学传感器研究”，福建省科学技术厅，青年项目（主持）

教学:

1. ESE336 - 环境分析化学（本科生）

2. ESE5096 - 环境生物分析化学（研究生）

学术成果：

代表性论文

(1) Zhimin Fan; Zusen Chen; Zhengwen Gong; Sanjun Shi; Mingdi Xu; Xiaonan Feng; Yulu Liu; Ya Hu; Xiaoduo Chen; Guomao Zheng; Bintian Zhang, Real-time electrical monitoring of enzymatic catalytic dynamics at the single-molecule level. Nature Communications 2026, 17, 7198.

(2) Mingdi Xu; Zhimin Fan; Ya Hu; Xiaonan Feng; Yulu Liu; Sirui Zhu; Jingjing Yu; Kun Zhang; Guomao Zheng; Bintian Zhang, Effect-Based Photoelectrochemical Screening of Estrogenic Activity in Wastewater via Cell-Free ERα-ERE Assembly. Analytical Chemistry 2026, 98, 19835−19846.

(3) Xiaonan Feng; Xiaoduo Chen; Kun Zhang; Zhimin Fan; Sanjun Shi; Ya Hu; Sheng Wan; Guomao Zheng; Bintian Zhang, Rapid and Highly Selective Detection of the Tire Antioxidant 6PPD in Water Samples via Dual-Mode Fluorescent and Photoelectrochemical Sensing Based on Host–Guest Recognition. Environmental Science & Technology 2026, 60, 14318-14328.

(4) Kun Zhang; Han Yan; Xiaoduo Chen; Zusen Chen; Xiaonan Feng; Ya Hu; Zheqian Chen; Xiaoyuan Guo; Chuanzi Gao; Yanzhou Bao; Jizhou Wu; Bintian Zhang, Electrochemical sensing of cationic per-and polyfluoroalkyl substances via dual-signal transduction. Sensors and Actuators B: Chemical 2026, 139852.

(5) Kun Zhang; Xiaonan Feng; Chuanzi Gao; Yulong Ma; Yuqing Dai; Zheqian Chen; Zhimin Fan; Xiaoyuan Guo; Tianhao Yang; Shangqing Wang; Mingdi Xu; Bintian Zhang, Polymerizable monomer for selective PFAS capture via fluorophilic interaction and cavity recognition: Rational design and applications in removal and sensing. Chemical Engineering Journal 2026, 176434.

(6) Zhimin Fan; Miao Chen; Jie Xiang; Bintian Zhang, Single-Molecule Conductance of Non-Redox Proteins: Mechanisms, Measurements, and Applications. Biomolecules 2026, 16, 495.

(7) Kun Zhang; Zhilin Guo; Ya Hu; Han Yan; Yanzhou Bao; Bintian Zhang, Supramolecular interactions in luminescent sensing of per-and polyfluoroalkyl substances (PFAS). Trends in Environmental Analytical Chemistry 2025, e00286.

(8) Xiaonan Feng; Sirui Zhu; Kun Zhang; Mingdi Xu; Zheqian Chen; Shangqing Wang; Jingjing Yao; Xiaoduo Chen; Bintian Zhang, Universal and highly efficient organic-inorganic heterojunctions enabled by a dual-functional polymer for photoelectrochemical detection of perfluorooctane sulfonate. Sensors and Actuators B: Chemical 2025, 138563.

(9) Chongchong Qi; Tao Hu; Yi Zheng; Mengting Wu; Fiona HM Tang; Min Liu; Bintian Zhang; Sybil Derrible; Qiusong Chen; Gongren Hu; Liyuan Chai, Zhang Lin, Global and regional patterns of soil metal (loid) mobility and associated risks. Nature Communications 2025, 16, 2947.

(10) Xiaonan Feng; Kun Zhang; Xiaoduo Chen; Yuemei Liang; Ya Hu; Yulu Liu; Chuanzi Gao; Feng Quan; Bintian Zhang, Engineering a plasmon-enhanced Z-scheme CdIn2S4/Bi2WO6 heterojunction for photoelectrochemical aptasensing of bisphenol S. Journal of Analysis and Testing 2025, 9, 538-547.

(11) Shangqing Wang; Lulu Ma; Xiaonan Feng; Kun Zhang; Zheqian Chen; Min Hu; Guomao Zheng; Yan Zheng; Bintian Zhang, Portable and Cost-Effective Detection of Perfluorooctanesulfonate in Water Using a Screen-Printed Electrode Modified with Molecularly Imprinted Polymer. ACS ES&T Water 2025, 5, 1261-1269.

(12) Jingjing Yao; Xiaonan Feng; Shangqing Wang; Yuemei Liang; Bintian Zhang, Plasmon-Enhanced Photoelectrochemistry of Photosystem II on a Hierarchical Tin Oxide Electrode for Ultrasensitive Detection of 17β-Estradiol. Analytical Chemistry 2024, 96, 18029-18036.

(13) Zhimin Fan; Kun Zhang; Xiaonan Feng; Ya Hu; Zheqian Chen; Shangqing Wang; Jingfu Liu; Bintian Zhang, Portable and ultrasensitive detection of traces of water in alcoholic solvents by a polypyrrole-modified screen-printed electrode. Journal of Electroanalytical Chemistry 2024, 970.

(14) Tao Jiang; Biao-Feng Zeng; Bintian Zhang; Longhua Tang, Single-molecular protein-based bioelectronics via electronic transport: fundamentals, devices and applications. Chemical Society Reviews 2023, 52, 5968-6002.

(15) Bintian Zhang; Eathen Ryan; Xu Wang; Weisi Song; Stuart Lindsay, Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins. ACS Nano 2022, 16, 1671-1680.

(16) Longhua Tang; Long Yi; Tao Jiang; Ren Ren; Binoy Paulose Nadappuram; Bintian Zhang; Jian Wu; Xu Liu; Stuart Lindsay; Joshua B. Edel; Aleksandar P. Ivanov, Measuring conductance switching in single proteins using quantum tunneling. Science Advances 2022, 8.

(17) Bintian Zhang; Eathen Ryan; Xu Wang; Stuart Lindsay, Probing Bioelectronic Connections Using Streptavidin Molecules with Modified Valency. Journal of the American Chemical Society 2021, 143, 15139-15144.

(18) Bintian Zhang; Weisi Song; Jesse Brown; Robert Nemanich; Stuart Lindsay, Electronic Conductance Resonance in Non-Redox-Active Proteins. Journal of the American Chemical Society 2020, 142, 6432-6438.

(19) Bintian Zhang; Hanqing Ding; Sohini Mukherjee; Weisi Song; Xu Wang; Stuart Lindsay, Engineering an Enzyme for Direct Electrical Monitoring of Activity. ACS Nano 2020, 14, 1360-1368.

(20) Bintian Zhang; Weisi Song; Pei Pang; Huafang Lai; Qiang Chen; Peiming Zhang; Stuart Lindsay, Role of contacts in long-range protein conductance. Proceedings of the National Academy of Sciences of the United States of America 2019, 116, 5886-5891.

(21) Bintian Zhang; Stuart Lindsay, Electronic Decay Length in a Protein Molecule. Nano Letters 2019, 19, 4017-4022.

(22) Bintian Zhang; Weisi Song; Pei Pang; Yanan Zhao; Peiming Zhang; Istvan Csabai; Gabor Vattay; Stuart Lindsay, Observation of giant conductance fluctuations in a protein. Nano Futures 2017, 1.

(23) Bintian Zhang; Lili Lu; Feng Huang; Zhang Lin, Ru(bpy)₃ ²⁺-mediated photoelectrochemical detection of bisphenol A on a molecularly imprinted polypyrrole modified SnO₂ electrode. Analytica Chimica Acta 2015, 887, 59-66.

(24) Yiping Wu; Xiqiang Yang; Bintian Zhang; Liang-Hong Guo, An electrochemiluminescence biosensor for 8-oxo-7,8-dihydro-2′-deoxyguanosine quantification and DNA repair enzyme activity analysis using a novel bifunctional probe. Biosensors & Bioelectronics 2015, 69, 235-240.

(25) Lili Lu; Xianyang Yue; Fuquan Lin; Feng Huang; Bintian Zhang; Zhang Lin, Template-synthesized ultra-thin molecularly imprinted polymers membrane for the selective preconcentration of dyes. Journal of Materials Chemistry A 2015, 3, 10959-10968.

(26) Bintian Zhang; Lili Lu; Qichang Hu; Feng Huang; Zhang Lin, ZnO nanoflower-based photoelectrochemical DNAzyme sensor for the detection of Pb²⁺. Biosensors & Bioelectronics 2014, 56, 243-249.

(27) Yiping Wu; Bintian Zhang; Liang-Hong Guo, Label-Free and Selective Photoelectrochemical Detection of Chemical DNA Methylation Damage Using DNA Repair Enzymes. Analytical Chemistry 2013, 85, 6908-6914.

(28) Min-Jie Li; Yi-Ping Wu; Bin-Tian Zhang; Liang-Hong Guo, Detection and Application of DNA Abasic Sites. Chinese Journal of Analytical Chemistry 2013, 41, 965-972.

(29) Bintian Zhang; Liang-Hong Guo; Marc M. Greenberg, Quantification of 8-OxodGuo Lesions in Double-Stranded DNA Using a Photoelectrochemical DNA Sensor. Analytical Chemistry 2012, 84, 6048-6053.

(30) Bintian Zhang; Liang-Hong Guo, Highly sensitive and selective photoelectrochemical DNA sensor for the detection of Hg²⁺ in aqueous solutions. Biosensors & Bioelectronics 2012, 37, 112-115.

(31) BinTian Zhang; Xin Du; SuPing Jia; JunHui He; LiangHong Guo, Rapid assessment of DNA damage induced by polystyrene nanosphere suspension using a photoelectrochemical DNA sensor. Science China-Chemistry 2011, 54, 1260-1265.

代表性专利

1.“一种大气颗粒物氧化潜势的检测方法及系统”，张斌田，胡雅，申请号：2025118686432，2025 （中国专利）

2.“一种基于电化学-pH 协同调控的用于全氟化合物去除与回收的氟化聚合物及其制备方法与应用”，张斌田，张坤，申请号：2025117123242，2025 （中国专利）

3.“一种基于分子电导的DNA 损伤碱基检测方法、系统及终端”，张斌田, 刘雨露，石三俊，申请号：2025118686358，2025 （中国专利）

4.“一种基于环糊精主客体识别6PPD 与6PPD-Q 的传感检测应用及传感器”，张斌田，冯晓楠，申请号：2025118052988，2025 （中国专利）

5.“一种用于污染物毒性效应筛查的单分子蛋白电导检测方法”，张斌田，姚静静，刘雨露，公布号：CN120253923A，2025（中国专利）

6.“亲氟疏水功能单体及其合成方法与应用、检测电极及其制备方法”，张斌田，张坤，专利号：ZL 202411378938.7，2024（中国专利-授权）

7.“用于检测醇类溶剂中含水量的丝网印刷电极及其制备方法”，张斌田，张坤，范志敏，公布号：CN118465019 A，2024（中国专利）

8.“一种用于全氟烷基和多氟烷基物质检测的电极及其制备方法与应用”，张斌田，王尚卿，马璐璐，郑焰，公布号：CN117871631 A，2024（中国专利）

9. “Method for electronic detection and quantification of antibodies”, Stuart Lindsay，Bintian Zhang, WO2019217600A1, Nov. 14, 2021 (US/PCT)

10. “Bioelectronic circuits, systems and methods for preparing and using them”, Stuart Lindsay，Bintian Zhang，Hanqing Deng, WO2020160300A3, Sep. 10, 2020 (US/PCT)

11. “Direct electrical readout of nucleic acid sequences”, Stuart Lindsay，Bintian Zhang，Hanqing Deng, WO2020257654A1, Dec. 24, 2020 (US/PCT)

12. “Methods for sequencing biopolymers”, Stuart Lindsay, Eathen Ryan, Bintian Zhang, Xu Wang, US20220389502A1, Jun. 3, 2022 (US)